Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx

Background<p>Enteral Nutrition-Associated Diarrhea (ENAD) is a common complication in critically ill patients, significantly impacting clinical outcomes. Accurately predicting the risk of ENAD is crucial for early intervention and improving patient care.</p>Objective<p>This study a...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Xiaoying Liao (21159071) (author)
مؤلفون آخرون: Chunhua Li (18618) (author), Qunyan Liu (21596501) (author), Wang Xia (1565947) (author), Zhenglin Liu (19261930) (author), Jiamao Zhu (21596504) (author), Wei Hu (6560) (author), Qionghua Hong (9911361) (author)
منشور في: 2025
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_version_ 1852019069907107840
author Xiaoying Liao (21159071)
author2 Chunhua Li (18618)
Qunyan Liu (21596501)
Wang Xia (1565947)
Zhenglin Liu (19261930)
Jiamao Zhu (21596504)
Wei Hu (6560)
Qionghua Hong (9911361)
author2_role author
author
author
author
author
author
author
author_facet Xiaoying Liao (21159071)
Chunhua Li (18618)
Qunyan Liu (21596501)
Wang Xia (1565947)
Zhenglin Liu (19261930)
Jiamao Zhu (21596504)
Wei Hu (6560)
Qionghua Hong (9911361)
author_role author
dc.creator.none.fl_str_mv Xiaoying Liao (21159071)
Chunhua Li (18618)
Qunyan Liu (21596501)
Wang Xia (1565947)
Zhenglin Liu (19261930)
Jiamao Zhu (21596504)
Wei Hu (6560)
Qionghua Hong (9911361)
dc.date.none.fl_str_mv 2025-06-25T04:07:11Z
dc.identifier.none.fl_str_mv 10.3389/fnut.2025.1584717.s002
dc.relation.none.fl_str_mv https://figshare.com/articles/dataset/Table_2_Machine_learning-based_predictive_model_for_enteral_nutrition-associated_diarrhea_in_ICU_patients_and_its_nursing_applications_docx/29397359
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Clinical and Sports Nutrition
enteral nutrition-associated diarrhea
machine learning
random forest
feature importance
critically ill patients
dc.title.none.fl_str_mv Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
dc.type.none.fl_str_mv Dataset
info:eu-repo/semantics/publishedVersion
dataset
description Background<p>Enteral Nutrition-Associated Diarrhea (ENAD) is a common complication in critically ill patients, significantly impacting clinical outcomes. Accurately predicting the risk of ENAD is crucial for early intervention and improving patient care.</p>Objective<p>This study aims to develop and validate a machine learning (ML)-based risk prediction model for Enteral Nutrition-Associated Diarrhea (ENAD) in ICU patients, and explore its application in nursing practice.</p>Method<p>This study was conducted from January 2023 to October 2024 in the Comprehensive Intensive Care Unit (ICU) of a tertiary hospital in China, retrospectively analyzing data from ICU patients receiving enteral nutrition. LASSO regression was used for feature selection, and 9 machine learning (ML) algorithms were evaluated. Model performance was assessed using metrics such as the area under the receiver operating characteristic curve (AUC). The SHapley Additive exPlanation (SHAP) method was employed to interpret feature importance and determine the final model.</p>Results<p>Among the 9 ML models, the random forest (RF) model demonstrated the highest discriminative ability, achieving an AUC (95% CI) of 0.777 (0.702–0.830). After dimensionality reduction based on feature importance analysis, a simplified and interpretable RF model with 12 key predictors was established, yielding an AUC (95% CI) of 0.754 (0.685–0.823).</p>Conclusion<p>The RF-based predictive model developed in this study provides a reliable and interpretable tool for identifying the risk of ENAD in ICU patients, contributing to targeted nursing interventions and improved patient outcomes. The research highlights the potential of machine learning in enhancing clinical decision-making and personalized care.</p>
eu_rights_str_mv openAccess
id Manara_feedbbeef15dd9ebfdc331abc6583e40
identifier_str_mv 10.3389/fnut.2025.1584717.s002
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/29397359
publishDate 2025
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repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docxXiaoying Liao (21159071)Chunhua Li (18618)Qunyan Liu (21596501)Wang Xia (1565947)Zhenglin Liu (19261930)Jiamao Zhu (21596504)Wei Hu (6560)Qionghua Hong (9911361)Clinical and Sports Nutritionenteral nutrition-associated diarrheamachine learningrandom forestfeature importancecritically ill patientsBackground<p>Enteral Nutrition-Associated Diarrhea (ENAD) is a common complication in critically ill patients, significantly impacting clinical outcomes. Accurately predicting the risk of ENAD is crucial for early intervention and improving patient care.</p>Objective<p>This study aims to develop and validate a machine learning (ML)-based risk prediction model for Enteral Nutrition-Associated Diarrhea (ENAD) in ICU patients, and explore its application in nursing practice.</p>Method<p>This study was conducted from January 2023 to October 2024 in the Comprehensive Intensive Care Unit (ICU) of a tertiary hospital in China, retrospectively analyzing data from ICU patients receiving enteral nutrition. LASSO regression was used for feature selection, and 9 machine learning (ML) algorithms were evaluated. Model performance was assessed using metrics such as the area under the receiver operating characteristic curve (AUC). The SHapley Additive exPlanation (SHAP) method was employed to interpret feature importance and determine the final model.</p>Results<p>Among the 9 ML models, the random forest (RF) model demonstrated the highest discriminative ability, achieving an AUC (95% CI) of 0.777 (0.702–0.830). After dimensionality reduction based on feature importance analysis, a simplified and interpretable RF model with 12 key predictors was established, yielding an AUC (95% CI) of 0.754 (0.685–0.823).</p>Conclusion<p>The RF-based predictive model developed in this study provides a reliable and interpretable tool for identifying the risk of ENAD in ICU patients, contributing to targeted nursing interventions and improved patient outcomes. The research highlights the potential of machine learning in enhancing clinical decision-making and personalized care.</p>2025-06-25T04:07:11ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.3389/fnut.2025.1584717.s002https://figshare.com/articles/dataset/Table_2_Machine_learning-based_predictive_model_for_enteral_nutrition-associated_diarrhea_in_ICU_patients_and_its_nursing_applications_docx/29397359CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/293973592025-06-25T04:07:11Z
spellingShingle Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
Xiaoying Liao (21159071)
Clinical and Sports Nutrition
enteral nutrition-associated diarrhea
machine learning
random forest
feature importance
critically ill patients
status_str publishedVersion
title Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
title_full Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
title_fullStr Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
title_full_unstemmed Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
title_short Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
title_sort Table 2_Machine learning-based predictive model for enteral nutrition-associated diarrhea in ICU patients and its nursing applications.docx
topic Clinical and Sports Nutrition
enteral nutrition-associated diarrhea
machine learning
random forest
feature importance
critically ill patients