Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants

In the field of medical implants, enhancing the wettability of artificial surfaces is crucial for improving biocompatibility. This study investigates the potential of ozone nanobubble water, an aqueous solution known for its strong oxidizing and sterilizing properties, to modify the surface of titan...

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Main Author: Masayoshi Takahashi (2816038) (author)
Other Authors: Masahiro Nakazawa (20324590) (author), Takahiro Nishimoto (2727718) (author), Mitsuyuki Odajima (20324593) (author), Yasuyuki Shirai (17199329) (author), Shigetoshi Sugawa (17199332) (author)
Published: 2024
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_version_ 1852024923511324672
author Masayoshi Takahashi (2816038)
author2 Masahiro Nakazawa (20324590)
Takahiro Nishimoto (2727718)
Mitsuyuki Odajima (20324593)
Yasuyuki Shirai (17199329)
Shigetoshi Sugawa (17199332)
author2_role author
author
author
author
author
author_facet Masayoshi Takahashi (2816038)
Masahiro Nakazawa (20324590)
Takahiro Nishimoto (2727718)
Mitsuyuki Odajima (20324593)
Yasuyuki Shirai (17199329)
Shigetoshi Sugawa (17199332)
author_role author
dc.creator.none.fl_str_mv Masayoshi Takahashi (2816038)
Masahiro Nakazawa (20324590)
Takahiro Nishimoto (2727718)
Mitsuyuki Odajima (20324593)
Yasuyuki Shirai (17199329)
Shigetoshi Sugawa (17199332)
dc.date.none.fl_str_mv 2024-11-25T20:46:27Z
dc.identifier.none.fl_str_mv 10.1021/acs.langmuir.4c03339.s003
dc.relation.none.fl_str_mv https://figshare.com/articles/media/Impact_of_Bulk_Nanobubble_Water_on_a_TiO_sub_2_sub_Solid_Surface_A_Case_Study_for_Medical_Implants/27905050
dc.rights.none.fl_str_mv CC BY-NC 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Medicine
Neuroscience
Biotechnology
Inorganic Chemistry
Hematology
Space Science
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
∼ 10 nm
∼ 10 min
ozone nanobubble water
aqueous solution known
fresh implant material
solid shell composed
bulk nanobubble water
becomes hydrophobic within
term surface modification
inherent high wettability
2 </ sub
implant surfaces might
titanium dental implants
enhancing implant biocompatibility
implant surfaces
implant ’
solid surface
improving biocompatibility
dental implants
bulk nanobubbles
become hydrophobic
artificial surfaces
sustained hydrophilicity
surface properties
surface characteristics
substantial alteration
study investigates
study highlights
strong oxidizing
sterilizing properties
stabilizing agents
spherical particles
significant transformation
sharp contrast
promising avenue
previous study
particles could
organic matter
organic contaminants
one month
medical implants
likely due
initially hydrophilic
hydrophilicity induced
hydrophilic nanoshells
durability suggests
case study
capping agents
became superhydrophilic
average diameter
dc.title.none.fl_str_mv Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
dc.type.none.fl_str_mv Dataset
Media
info:eu-repo/semantics/publishedVersion
dataset
description In the field of medical implants, enhancing the wettability of artificial surfaces is crucial for improving biocompatibility. This study investigates the potential of ozone nanobubble water, an aqueous solution known for its strong oxidizing and sterilizing properties, to modify the surface of titanium dental implants. By immersing the implants in ozone nanobubble water for ∼10 min, we observed a significant transformation of their surface characteristics. Implant surfaces that had become hydrophobic over time, likely due to organic contaminants, became superhydrophilic, exhibiting a contact angle near zero. Fresh implant material is initially hydrophilic but becomes hydrophobic within a few days of drying. In sharp contrast, the hydrophilicity induced by ozone nanobubble water treatment persisted for more than one month. This durability suggests not only the removal of organic matter through cleaning but also a substantial alteration in the surface properties of the implants. The generation of ozone nanobubble water involved releasing ozone microbubbles into an aqueous solution containing trace amounts of iron and manganese, resulting in spherical particles with an average diameter of ∼10 nm. These particles could be bulk nanobubbles, a stabilized gas body surrounded by a solid shell composed of iron hydroxide. Termed “nanoshells” in our previous study, these particles demonstrated exceptional dispersibility without the need for stabilizing agents such as surfactants or capping agents, attributed to their inherent high wettability. The sustained hydrophilicity of the implant surfaces might be attributed to the adherence of these hydrophilic nanoshells to the implant’s surface. This study highlights the potential of ozone nanobubble water for long-term surface modification of dental implants, offering a promising avenue for enhancing implant biocompatibility.
eu_rights_str_mv openAccess
id Manara_fefbdda260d3bf4ebebfc7883645c0d2
identifier_str_mv 10.1021/acs.langmuir.4c03339.s003
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/27905050
publishDate 2024
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY-NC 4.0
spelling Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical ImplantsMasayoshi Takahashi (2816038)Masahiro Nakazawa (20324590)Takahiro Nishimoto (2727718)Mitsuyuki Odajima (20324593)Yasuyuki Shirai (17199329)Shigetoshi Sugawa (17199332)MedicineNeuroscienceBiotechnologyInorganic ChemistryHematologySpace ScienceEnvironmental Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedChemical Sciences not elsewhere classified∼ 10 nm∼ 10 minozone nanobubble wateraqueous solution knownfresh implant materialsolid shell composedbulk nanobubble waterbecomes hydrophobic withinterm surface modificationinherent high wettability2 </ subimplant surfaces mighttitanium dental implantsenhancing implant biocompatibilityimplant surfacesimplant ’solid surfaceimproving biocompatibilitydental implantsbulk nanobubblesbecome hydrophobicartificial surfacessustained hydrophilicitysurface propertiessurface characteristicssubstantial alterationstudy investigatesstudy highlightsstrong oxidizingsterilizing propertiesstabilizing agentsspherical particlessignificant transformationsharp contrastpromising avenueprevious studyparticles couldorganic matterorganic contaminantsone monthmedical implantslikely dueinitially hydrophilichydrophilicity inducedhydrophilic nanoshellsdurability suggestscase studycapping agentsbecame superhydrophilicaverage diameterIn the field of medical implants, enhancing the wettability of artificial surfaces is crucial for improving biocompatibility. This study investigates the potential of ozone nanobubble water, an aqueous solution known for its strong oxidizing and sterilizing properties, to modify the surface of titanium dental implants. By immersing the implants in ozone nanobubble water for ∼10 min, we observed a significant transformation of their surface characteristics. Implant surfaces that had become hydrophobic over time, likely due to organic contaminants, became superhydrophilic, exhibiting a contact angle near zero. Fresh implant material is initially hydrophilic but becomes hydrophobic within a few days of drying. In sharp contrast, the hydrophilicity induced by ozone nanobubble water treatment persisted for more than one month. This durability suggests not only the removal of organic matter through cleaning but also a substantial alteration in the surface properties of the implants. The generation of ozone nanobubble water involved releasing ozone microbubbles into an aqueous solution containing trace amounts of iron and manganese, resulting in spherical particles with an average diameter of ∼10 nm. These particles could be bulk nanobubbles, a stabilized gas body surrounded by a solid shell composed of iron hydroxide. Termed “nanoshells” in our previous study, these particles demonstrated exceptional dispersibility without the need for stabilizing agents such as surfactants or capping agents, attributed to their inherent high wettability. The sustained hydrophilicity of the implant surfaces might be attributed to the adherence of these hydrophilic nanoshells to the implant’s surface. This study highlights the potential of ozone nanobubble water for long-term surface modification of dental implants, offering a promising avenue for enhancing implant biocompatibility.2024-11-25T20:46:27ZDatasetMediainfo:eu-repo/semantics/publishedVersiondataset10.1021/acs.langmuir.4c03339.s003https://figshare.com/articles/media/Impact_of_Bulk_Nanobubble_Water_on_a_TiO_sub_2_sub_Solid_Surface_A_Case_Study_for_Medical_Implants/27905050CC BY-NC 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/279050502024-11-25T20:46:27Z
spellingShingle Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
Masayoshi Takahashi (2816038)
Medicine
Neuroscience
Biotechnology
Inorganic Chemistry
Hematology
Space Science
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
∼ 10 nm
∼ 10 min
ozone nanobubble water
aqueous solution known
fresh implant material
solid shell composed
bulk nanobubble water
becomes hydrophobic within
term surface modification
inherent high wettability
2 </ sub
implant surfaces might
titanium dental implants
enhancing implant biocompatibility
implant surfaces
implant ’
solid surface
improving biocompatibility
dental implants
bulk nanobubbles
become hydrophobic
artificial surfaces
sustained hydrophilicity
surface properties
surface characteristics
substantial alteration
study investigates
study highlights
strong oxidizing
sterilizing properties
stabilizing agents
spherical particles
significant transformation
sharp contrast
promising avenue
previous study
particles could
organic matter
organic contaminants
one month
medical implants
likely due
initially hydrophilic
hydrophilicity induced
hydrophilic nanoshells
durability suggests
case study
capping agents
became superhydrophilic
average diameter
status_str publishedVersion
title Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
title_full Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
title_fullStr Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
title_full_unstemmed Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
title_short Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
title_sort Impact of Bulk Nanobubble Water on a TiO<sub>2</sub> Solid Surface: A Case Study for Medical Implants
topic Medicine
Neuroscience
Biotechnology
Inorganic Chemistry
Hematology
Space Science
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
∼ 10 nm
∼ 10 min
ozone nanobubble water
aqueous solution known
fresh implant material
solid shell composed
bulk nanobubble water
becomes hydrophobic within
term surface modification
inherent high wettability
2 </ sub
implant surfaces might
titanium dental implants
enhancing implant biocompatibility
implant surfaces
implant ’
solid surface
improving biocompatibility
dental implants
bulk nanobubbles
become hydrophobic
artificial surfaces
sustained hydrophilicity
surface properties
surface characteristics
substantial alteration
study investigates
study highlights
strong oxidizing
sterilizing properties
stabilizing agents
spherical particles
significant transformation
sharp contrast
promising avenue
previous study
particles could
organic matter
organic contaminants
one month
medical implants
likely due
initially hydrophilic
hydrophilicity induced
hydrophilic nanoshells
durability suggests
case study
capping agents
became superhydrophilic
average diameter