Figure 2 from Metabolomic Biomarkers in Blood Samples Identify Cancers in a Mixed Population of Patients with Nonspecific Symptoms

Figure 2 from Metabolomic Biomarkers in Blood Samples Identify Cancers in a Mixed Population of Patients with Nonspecific Symptoms

<p><b>A,</b> Mean NMR spectra for samples from unwell patients with either confirmed solid tumor diagnoses (red, <i>n</i> = 17) or confirmed noncancer diagnoses (black, <i>n</i> = 175). <b>B,</b> Difference spectrum showing regions that were incr...

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Main Author: James R. Larkin (14936324) (author)
Other Authors: Susan Anthony (15039111) (author), Vanessa A. Johanssen (15039114) (author), Tianrong Yeo (15039117) (author), Megan Sealey (12045959) (author), Abi G. Yates (14029965) (author), Claire Friedemann Smith (15039120) (author), Timothy D.W. Claridge (15039123) (author), Brian D. Nicholson (2889917) (author), Julie-Ann Moreland (15039126) (author), Fergus Gleeson (4055239) (author), Nicola R. Sibson (14936336) (author), Daniel C. Anthony (15039129) (author), Fay Probert (849357) (author)
Published: 2025
Subjects:
Cancer
Molecular and Cellular Biology
Cancer Detection and Diagnosis
Methods and Technology
Biomarkers
Diagnostic biomarkers
Early detection biomarkers
Liquid Biopsy
Metabolism
Metabolomics
Tumor Staging
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Summary:<p><b>A,</b> Mean NMR spectra for samples from unwell patients with either confirmed solid tumor diagnoses (red, <i>n</i> = 17) or confirmed noncancer diagnoses (black, <i>n</i> = 175). <b>B,</b> Difference spectrum showing regions that were increased in patients with solid tumors (red), decreased in patients with solid tumors (blue), or unchanged (gray). <b>C,</b> Insets showing magnified regions at points of significant difference between unwell with solid tumor spectra (red) and unwell without cancer spectra (black). NAC, <i>N</i>-acetylated glycoproteins.</p>

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