The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms

The adipocyte-derived secretory protein adiponectin functions as an insulin-sensitizing agent. In plasma, adiponectin exists as low, medium, and high molecular weight oligomers. Treatment with trans-10, cis-12 conjugated linoleic acid (t-10, c-12 CLA) reduces levels of adiponectin as well as triglyc...

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Bibliographic Details
Main Author: Miller, Jessica R. (author)
Other Authors: Siripurkpong, Pilaiwan (author), Hawes, Jennifer (author), Majdalawieh, Amin (author), Ro, Hyo-Sung (author), McLeod, Roger S. (author)
Format: article
Published: 2008
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Online Access:http://hdl.handle.net/11073/25063
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