Toxicological impact of nanoparticles on human health: A review

Nanotechnology is a rapidly growing industry where nanomaterials are used in almost every field, including electronics, cosmetics, engineering, household products, biotechnology and medicine. Nanoparticles (NPs) have unique physical and chemical properties, which may cause potential hazards to human...

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Main Author: Mohamed, Omnia A. (author)
Other Authors: Ajith, Saniha Aysha (author), Sabouni, Rana (author), Husseini, Ghaleb (author), Karami, Abdollah (author), Bai, Renu Geetha (author)
Format: article
Published: 2022
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Online Access:http://hdl.handle.net/11073/23634
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author Mohamed, Omnia A.
author2 Ajith, Saniha Aysha
Sabouni, Rana
Husseini, Ghaleb
Karami, Abdollah
Bai, Renu Geetha
author2_role author
author
author
author
author
author_facet Mohamed, Omnia A.
Ajith, Saniha Aysha
Sabouni, Rana
Husseini, Ghaleb
Karami, Abdollah
Bai, Renu Geetha
author_role author
dc.creator.none.fl_str_mv Mohamed, Omnia A.
Ajith, Saniha Aysha
Sabouni, Rana
Husseini, Ghaleb
Karami, Abdollah
Bai, Renu Geetha
dc.date.none.fl_str_mv 2022-05-17T07:52:57Z
2022-05-17T07:52:57Z
2022
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv Mohamed, O; Ajith, S; Sabouni, R; Husseini,G; Karami, A; Bai, R. (2022) Toxicological impact of nanoparticles on human health: A review. Materials Express, 12. https://doi.org/10.1166/mex.2022.2161
2158-5849
http://hdl.handle.net/11073/23634
10.1166/mex.2022.2161
dc.language.none.fl_str_mv en_US
dc.publisher.none.fl_str_mv American Scientific Publishers
dc.relation.none.fl_str_mv https://doi.org/10.1166/mex.2022.2161
dc.subject.none.fl_str_mv Nanoparticles
Health Hazard
Physiology
Exposure Limits
Routes of Exposure
Cytotoxicity
dc.title.none.fl_str_mv Toxicological impact of nanoparticles on human health: A review
dc.type.none.fl_str_mv Peer-Reviewed
Postprint
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Nanotechnology is a rapidly growing industry where nanomaterials are used in almost every field, including electronics, cosmetics, engineering, household products, biotechnology and medicine. Nanoparticles (NPs) have unique physical and chemical properties, which may cause potential hazards to human health, especially with constant exposure. Various studies have shown that NPs can enter the human body either through the respiratory tract, dermal absorption or via the gastrointestinal system and have the potential to cause respiratory disorders, behavioral changes, neurological disorders, as well as cancer. This review focuses on the health implications of NPs, specifically gold, silver, silica, titanium dioxide, aluminum, aluminum oxides, metal organic frameworks (MOF), aerosol particles, flame retardants, quantum dots, and carbon nanotubes. Herein, we discuss the routes of exposure and the impact of these nanoparticles on human health. We also summarize in-vitro and in-vivo studies that analyze the cytotoxicity profile and the associated health impact of these nanoparticles. This study could be utilized to develop well-defined guidelines for setting exposure limits for different NP types as well as a summary of related characteristics such as size, shape, morphology, and surface charge.
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identifier_str_mv Mohamed, O; Ajith, S; Sabouni, R; Husseini,G; Karami, A; Bai, R. (2022) Toxicological impact of nanoparticles on human health: A review. Materials Express, 12. https://doi.org/10.1166/mex.2022.2161
2158-5849
10.1166/mex.2022.2161
language_invalid_str_mv en_US
network_acronym_str aus
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oai_identifier_str oai:repository.aus.edu:11073/23634
publishDate 2022
publisher.none.fl_str_mv American Scientific Publishers
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spelling Toxicological impact of nanoparticles on human health: A reviewMohamed, Omnia A.Ajith, Saniha AyshaSabouni, RanaHusseini, GhalebKarami, AbdollahBai, Renu GeethaNanoparticlesHealth HazardPhysiologyExposure LimitsRoutes of ExposureCytotoxicityNanotechnology is a rapidly growing industry where nanomaterials are used in almost every field, including electronics, cosmetics, engineering, household products, biotechnology and medicine. Nanoparticles (NPs) have unique physical and chemical properties, which may cause potential hazards to human health, especially with constant exposure. Various studies have shown that NPs can enter the human body either through the respiratory tract, dermal absorption or via the gastrointestinal system and have the potential to cause respiratory disorders, behavioral changes, neurological disorders, as well as cancer. This review focuses on the health implications of NPs, specifically gold, silver, silica, titanium dioxide, aluminum, aluminum oxides, metal organic frameworks (MOF), aerosol particles, flame retardants, quantum dots, and carbon nanotubes. Herein, we discuss the routes of exposure and the impact of these nanoparticles on human health. We also summarize in-vitro and in-vivo studies that analyze the cytotoxicity profile and the associated health impact of these nanoparticles. This study could be utilized to develop well-defined guidelines for setting exposure limits for different NP types as well as a summary of related characteristics such as size, shape, morphology, and surface charge.American University of SharjahSheikh Hamdan Award for Medical SciencesFriends of Cancer PatientsAmerican Scientific Publishers2022-05-17T07:52:57Z2022-05-17T07:52:57Z2022Peer-ReviewedPostprintinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMohamed, O; Ajith, S; Sabouni, R; Husseini,G; Karami, A; Bai, R. (2022) Toxicological impact of nanoparticles on human health: A review. Materials Express, 12. https://doi.org/10.1166/mex.2022.21612158-5849http://hdl.handle.net/11073/2363410.1166/mex.2022.2161en_UShttps://doi.org/10.1166/mex.2022.2161oai:repository.aus.edu:11073/236342024-08-22T12:04:37Z
spellingShingle Toxicological impact of nanoparticles on human health: A review
Mohamed, Omnia A.
Nanoparticles
Health Hazard
Physiology
Exposure Limits
Routes of Exposure
Cytotoxicity
status_str publishedVersion
title Toxicological impact of nanoparticles on human health: A review
title_full Toxicological impact of nanoparticles on human health: A review
title_fullStr Toxicological impact of nanoparticles on human health: A review
title_full_unstemmed Toxicological impact of nanoparticles on human health: A review
title_short Toxicological impact of nanoparticles on human health: A review
title_sort Toxicological impact of nanoparticles on human health: A review
topic Nanoparticles
Health Hazard
Physiology
Exposure Limits
Routes of Exposure
Cytotoxicity
url http://hdl.handle.net/11073/23634