Carbohydrate-Functionalized Liposomes In Cancer Therapy
Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based platforms for the delivery of anticancer drugs. Among these nanocarriers, liposomes...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| التنسيق: | article |
| منشور في: |
2020
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://hdl.handle.net/11073/19720 |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513434970750976 |
|---|---|
| author | AlSawaftah, Nour Majdi |
| author2 | Abusamra, Rand Hasan Husseini, Ghaleb |
| author2_role | author author |
| author_facet | AlSawaftah, Nour Majdi Abusamra, Rand Hasan Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | AlSawaftah, Nour Majdi Abusamra, Rand Hasan Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2020-08-17T09:10:34Z 2020-08-17T09:10:34Z 2020 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | AlSawaftah, N. M., Abusamra, R. H., & Husseini, G. A. (2020). Carbohydrate-functionalized liposomes In cancer therapy. Current Cancer Therapy Reviews, 16, 1-17. doi: 10.2174/1573394716999200626144921 1573-3947 http://hdl.handle.net/11073/19720 10.2174/1573394716999200626144921 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | Bentham Science |
| dc.relation.none.fl_str_mv | http://dx.doi.org/10.2174/1573394716999200626144921 |
| dc.subject.none.fl_str_mv | Carbohydrate Liposomes Cancer Receptor Glycan Glycoliposome |
| dc.title.none.fl_str_mv | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| dc.type.none.fl_str_mv | Peer-Reviewed Postprint info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based platforms for the delivery of anticancer drugs. Among these nanocarriers, liposomes have demonstrated excellent potential in drug delivery applications. Furthermore, the overexpression of certain receptors on cancer cells has led to the development of active targeting approaches where liposome surfaces are decorated with ligands against these receptors. Given the central role that sugars play in cancer biology, more and more researchers are integrating "glycoscience" into their anticancer therapeutic designs. Carbohydrate functionalized liposomes present an attractive drug delivery system due to their biocompatibility, biodegradability, low toxicity, and specific cell targeting ability. This review presents an overview of the preparation methods, characterization, evaluation, and applications of carbohydrate functionalized liposomes in cancer therapy. |
| format | article |
| id | aus_2ee48901bbc91845e3a891745b07fb59 |
| identifier_str_mv | AlSawaftah, N. M., Abusamra, R. H., & Husseini, G. A. (2020). Carbohydrate-functionalized liposomes In cancer therapy. Current Cancer Therapy Reviews, 16, 1-17. doi: 10.2174/1573394716999200626144921 1573-3947 10.2174/1573394716999200626144921 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/19720 |
| publishDate | 2020 |
| publisher.none.fl_str_mv | Bentham Science |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Carbohydrate-Functionalized Liposomes In Cancer TherapyAlSawaftah, Nour MajdiAbusamra, Rand HasanHusseini, GhalebCarbohydrateLiposomesCancerReceptorGlycanGlycoliposomeExisting cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based platforms for the delivery of anticancer drugs. Among these nanocarriers, liposomes have demonstrated excellent potential in drug delivery applications. Furthermore, the overexpression of certain receptors on cancer cells has led to the development of active targeting approaches where liposome surfaces are decorated with ligands against these receptors. Given the central role that sugars play in cancer biology, more and more researchers are integrating "glycoscience" into their anticancer therapeutic designs. Carbohydrate functionalized liposomes present an attractive drug delivery system due to their biocompatibility, biodegradability, low toxicity, and specific cell targeting ability. This review presents an overview of the preparation methods, characterization, evaluation, and applications of carbohydrate functionalized liposomes in cancer therapy.Bentham Science2020-08-17T09:10:34Z2020-08-17T09:10:34Z2020Peer-ReviewedPostprintinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfAlSawaftah, N. M., Abusamra, R. H., & Husseini, G. A. (2020). Carbohydrate-functionalized liposomes In cancer therapy. Current Cancer Therapy Reviews, 16, 1-17. doi: 10.2174/15733947169992006261449211573-3947http://hdl.handle.net/11073/1972010.2174/1573394716999200626144921en_UShttp://dx.doi.org/10.2174/1573394716999200626144921oai:repository.aus.edu:11073/197202024-08-22T12:06:24Z |
| spellingShingle | Carbohydrate-Functionalized Liposomes In Cancer Therapy AlSawaftah, Nour Majdi Carbohydrate Liposomes Cancer Receptor Glycan Glycoliposome |
| status_str | publishedVersion |
| title | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| title_full | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| title_fullStr | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| title_full_unstemmed | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| title_short | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| title_sort | Carbohydrate-Functionalized Liposomes In Cancer Therapy |
| topic | Carbohydrate Liposomes Cancer Receptor Glycan Glycoliposome |
| url | http://hdl.handle.net/11073/19720 |