Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation

A Master of Science thesis in Computer Engineering by Khaldoon Alhusari entitled, “Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation”, submitted in November 2023. Thesis advisor is Dr. Salam Dhou. Soft copy is available (Thesis, Completion Certificate, Approval Signatures...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Alhusari, Khaldoon (author)
التنسيق: doctoralThesis
منشور في: 2023
الموضوعات:
الوصول للمادة أونلاين:http://hdl.handle.net/11073/25471
الوسوم: إضافة وسم
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author Alhusari, Khaldoon
author_facet Alhusari, Khaldoon
author_role author
dc.contributor.none.fl_str_mv Dhou, Salam
dc.creator.none.fl_str_mv Alhusari, Khaldoon
dc.date.none.fl_str_mv 2023-11
2024-02-28T08:18:46Z
2024-02-28T08:18:46Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv 35.232-2023.62
http://hdl.handle.net/11073/25471
dc.language.none.fl_str_mv en_US
dc.subject.none.fl_str_mv Breast Cancer
Breast Density
Mammograms
Unsupervised Learning
Segmentation
Inter-observer Variability
dc.title.none.fl_str_mv Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/doctoralThesis
description A Master of Science thesis in Computer Engineering by Khaldoon Alhusari entitled, “Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation”, submitted in November 2023. Thesis advisor is Dr. Salam Dhou. Soft copy is available (Thesis, Completion Certificate, Approval Signatures, and AUS Archives Consent Form).
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language_invalid_str_mv en_US
network_acronym_str aus
network_name_str aus
oai_identifier_str oai:repository.aus.edu:11073/25471
publishDate 2023
repository.mail.fl_str_mv
repository.name.fl_str_mv
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spelling Breast Density Estimation in Mammograms Using Unsupervised Image SegmentationAlhusari, KhaldoonBreast CancerBreast DensityMammogramsUnsupervised LearningSegmentationInter-observer VariabilityA Master of Science thesis in Computer Engineering by Khaldoon Alhusari entitled, “Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation”, submitted in November 2023. Thesis advisor is Dr. Salam Dhou. Soft copy is available (Thesis, Completion Certificate, Approval Signatures, and AUS Archives Consent Form).Breast cancer, the most prevalent cancer in women as of 2020, poses significant health risks. Early detection is crucial for effective management, and mammography serves as a key screening method. Mammograms, produced through mammography, are x-ray images which allow radiologists to assess mammographic density—a measure of non-fatty tissue in the breast. The Breast Imaging-Reporting and Data System (BI-RADS) is the current standard for density measurement, and it categorizes density into four classes. The importance of studying breast density is twofold. First, high breast density can be a factor in lowering the mammogram sensitivity as dense tissue, which looks bright on a mammogram, can mask cancers in mammograms. Second, higher breast density is associated with an increased risk of breast cancer, making accurate assessments vital. However, challenges arise in interpreting mammograms, particularly regarding inter-observer variability, especially with dense breasts. This work addresses the need for accurate and objective breast density assessments. It proposes a label-noise-tolerant unsupervised-learning-based method for quantitative breast density estimation. The study begins with a comprehensive review of existing literature and state-of-the-art techniques. A framework for breast density estimation is then introduced, involving mammogram preprocessing, unsupervised segmentation, and percentage density estimation. A convolutional neural network (CNN) with a loss function combining similarity and continuity is adapted for segmentation. The framework is tested on two public datasets (DDSM and INbreast), and its segmentation quality, classification capability, and unsupervised labeling ability are evaluated. Silhouette scores exceed 0.92 for subsets of both datasets, demonstrating strong segmentation performance. Per-patient agreements of 71.43% and 79.28% are achieved for DDSM and INbreast datasets, respectively, comparable to state-of-the-art techniques. The clustering quality assessment confirms reasonable unsupervised labeling, with Silhouette scores averaging around 0.57 for DDSM and 0.50 for INbreast. The proposed framework provides a non-subjective model for quantitative breast density estimation. Its potential benefits extend to clinical settings, where it can aid radiologists in assessing breast density.College of EngineeringDepartment of Computer Science and EngineeringMaster of Science in Computer Engineering (MSCoE)Dhou, Salam2024-02-28T08:18:46Z2024-02-28T08:18:46Z2023-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdf35.232-2023.62http://hdl.handle.net/11073/25471en_USoai:repository.aus.edu:11073/254712025-06-26T12:22:06Z
spellingShingle Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
Alhusari, Khaldoon
Breast Cancer
Breast Density
Mammograms
Unsupervised Learning
Segmentation
Inter-observer Variability
status_str publishedVersion
title Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
title_full Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
title_fullStr Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
title_full_unstemmed Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
title_short Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
title_sort Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
topic Breast Cancer
Breast Density
Mammograms
Unsupervised Learning
Segmentation
Inter-observer Variability
url http://hdl.handle.net/11073/25471