Phase transitions of nanoemulsions using ultrasound: Experimental observations

The ultrasound-induced transformation of perfluorocarbon liquids to gases is of interest in the area of drug and gene delivery. In this study, three independent parameters (temperature, size, and perfluorocarbon species) were selected to investigate the effects of 476-kHz and 20-kHz ultrasound on na...

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Main Author: Singh, Ram (author)
Other Authors: Husseini, Ghaleb (author), Pitt, William G. (author)
Format: article
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/11073/21294
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author Singh, Ram
author2 Husseini, Ghaleb
Pitt, William G.
author2_role author
author
author_facet Singh, Ram
Husseini, Ghaleb
Pitt, William G.
author_role author
dc.creator.none.fl_str_mv Singh, Ram
Husseini, Ghaleb
Pitt, William G.
dc.date.none.fl_str_mv 2012
2021-01-28T05:45:19Z
2021-01-28T05:45:19Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv Ram Singh, Ghaleb A. Husseini, William G. Pitt, Phase transitions of nanoemulsions using ultrasound: Experimental observations, Ultrasonics Sonochemistry, Volume 19, Issue 5, 2012, Pages 1120-1125, ISSN 1350-4177, https://doi.org/10.1016/j.ultsonch.2012.02.005.
1350-4177
http://hdl.handle.net/11073/21294
10.1016/j.ultsonch.2012.02.005
dc.language.none.fl_str_mv en_US
dc.publisher.none.fl_str_mv Elsevier
dc.relation.none.fl_str_mv https://doi.org/10.1016/j.ultsonch.2012.02.005
dc.subject.none.fl_str_mv Perfluorocarbons
Ultrasound
Cavitation
Nanoemulsions
Microbubbles
dc.title.none.fl_str_mv Phase transitions of nanoemulsions using ultrasound: Experimental observations
dc.type.none.fl_str_mv Peer-Reviewed
Published version
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description The ultrasound-induced transformation of perfluorocarbon liquids to gases is of interest in the area of drug and gene delivery. In this study, three independent parameters (temperature, size, and perfluorocarbon species) were selected to investigate the effects of 476-kHz and 20-kHz ultrasound on nanoemulsion phase transition. Two levels of each factor (low and high) were considered at each frequency. The acoustic intensities at gas bubble formation and at the onset of inertial cavitation were recorded and subsequently correlated with the acoustic parameters. Experimental data showed that low frequencies are more effective in forming and collapsing a bubble. Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions.
format article
id aus_67045d1216ab7ad282e9bee38dee4c87
identifier_str_mv Ram Singh, Ghaleb A. Husseini, William G. Pitt, Phase transitions of nanoemulsions using ultrasound: Experimental observations, Ultrasonics Sonochemistry, Volume 19, Issue 5, 2012, Pages 1120-1125, ISSN 1350-4177, https://doi.org/10.1016/j.ultsonch.2012.02.005.
1350-4177
10.1016/j.ultsonch.2012.02.005
language_invalid_str_mv en_US
network_acronym_str aus
network_name_str aus
oai_identifier_str oai:repository.aus.edu:11073/21294
publishDate 2012
publisher.none.fl_str_mv Elsevier
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
spelling Phase transitions of nanoemulsions using ultrasound: Experimental observationsSingh, RamHusseini, GhalebPitt, William G.PerfluorocarbonsUltrasoundCavitationNanoemulsionsMicrobubblesThe ultrasound-induced transformation of perfluorocarbon liquids to gases is of interest in the area of drug and gene delivery. In this study, three independent parameters (temperature, size, and perfluorocarbon species) were selected to investigate the effects of 476-kHz and 20-kHz ultrasound on nanoemulsion phase transition. Two levels of each factor (low and high) were considered at each frequency. The acoustic intensities at gas bubble formation and at the onset of inertial cavitation were recorded and subsequently correlated with the acoustic parameters. Experimental data showed that low frequencies are more effective in forming and collapsing a bubble. Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions.Elsevier2021-01-28T05:45:19Z2021-01-28T05:45:19Z2012Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfRam Singh, Ghaleb A. Husseini, William G. Pitt, Phase transitions of nanoemulsions using ultrasound: Experimental observations, Ultrasonics Sonochemistry, Volume 19, Issue 5, 2012, Pages 1120-1125, ISSN 1350-4177, https://doi.org/10.1016/j.ultsonch.2012.02.005.1350-4177http://hdl.handle.net/11073/2129410.1016/j.ultsonch.2012.02.005en_UShttps://doi.org/10.1016/j.ultsonch.2012.02.005oai:repository.aus.edu:11073/212942024-08-22T12:04:42Z
spellingShingle Phase transitions of nanoemulsions using ultrasound: Experimental observations
Singh, Ram
Perfluorocarbons
Ultrasound
Cavitation
Nanoemulsions
Microbubbles
status_str publishedVersion
title Phase transitions of nanoemulsions using ultrasound: Experimental observations
title_full Phase transitions of nanoemulsions using ultrasound: Experimental observations
title_fullStr Phase transitions of nanoemulsions using ultrasound: Experimental observations
title_full_unstemmed Phase transitions of nanoemulsions using ultrasound: Experimental observations
title_short Phase transitions of nanoemulsions using ultrasound: Experimental observations
title_sort Phase transitions of nanoemulsions using ultrasound: Experimental observations
topic Perfluorocarbons
Ultrasound
Cavitation
Nanoemulsions
Microbubbles
url http://hdl.handle.net/11073/21294