Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair
Biomedical devices made from high-modulus and hardness materials play a critical role in enhancing the quality of life for people with bone-related ailments. While these materials have been successfully used in orthopedic applications, concerns including stress-shielding have necessitated the explor...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| التنسيق: | article |
| منشور في: |
2023
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://hdl.handle.net/11073/25429 |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513432896667648 |
|---|---|
| author | Thomas, Kevin Koshy |
| author2 | Zafar, Mah Noor Pitt, William G. |
| author2_role | author author |
| author_facet | Thomas, Kevin Koshy Zafar, Mah Noor Pitt, William G. |
| author_role | author |
| dc.creator.none.fl_str_mv | Thomas, Kevin Koshy Zafar, Mah Noor Pitt, William G. |
| dc.date.none.fl_str_mv | 2023-12-20T05:00:00Z 2023-12-20T05:00:00Z 2023-12-19 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Thomas, K. K., Zafar, M. N., Pitt, W. G., & Husseini, G. A. (2023). Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair. In Applied Sciences (Vol. 14, Issue 1, p. 10). MDPI AG. https://doi.org/10.3390/app14010010 2076-3417 http://hdl.handle.net/11073/25429 10.3390/app14010010 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | MDPI |
| dc.relation.none.fl_str_mv | https://doi.org/10.3390/app14010010 |
| dc.subject.none.fl_str_mv | Magnesium alloys Biomaterials Biomedical implants |
| dc.title.none.fl_str_mv | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| dc.type.none.fl_str_mv | Peer-Reviewed Published version info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Biomedical devices made from high-modulus and hardness materials play a critical role in enhancing the quality of life for people with bone-related ailments. While these materials have been successfully used in orthopedic applications, concerns including stress-shielding have necessitated the exploration of alternative solutions. An ideal biomedical implant requires a delicate balance of mechanical performance, corrosion resistance, tissue biocompatibility, and other properties such as tribological performance and osseointegration. This review explores the suitability of biodegradable magnesium (Mg) alloys as a promising material for biomedical implants. It delves into the essential properties of biomedical implants, emphasizing the importance of matching mechanical characteristics with human bone properties to mitigate stress shielding. The corrosion properties of implant materials are discussed, highlighting the need for controlled degradation to ensure the safety and longevity of implants. The focus then shifts to the potential of magnesium alloys as biomedical implants, examining their benefits, limitations, and the challenges associated with their high degradation rates and less-than-satisfactory mechanical properties. Alloying with elements such as aluminum, zinc, and others is explored to improve magnesium alloys’ mechanical performance and corrosion resistance. Furthermore, this review discusses surface modification techniques, including chemical conversion coatings and biomimetic deposition, as effective strategies to enhance the corrosion resistance and biocompatibility of magnesium and its alloys. These modifications offer opportunities to improve the long-term performance of magnesium-based biomedical implants. This review provides a comprehensive overview of the properties, challenges, and potential solutions associated with biodegradable magnesium alloys as a promising material for biomedical implants. It underscores the importance of addressing problems related to mechanical performance, corrosion resistance, and biocompatibility to advance the development of safe and effective biomedical implant materials. |
| format | article |
| id | aus_761a7c52f46d92af95d40d610c362d68 |
| identifier_str_mv | Thomas, K. K., Zafar, M. N., Pitt, W. G., & Husseini, G. A. (2023). Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair. In Applied Sciences (Vol. 14, Issue 1, p. 10). MDPI AG. https://doi.org/10.3390/app14010010 2076-3417 10.3390/app14010010 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/25429 |
| publishDate | 2023 |
| publisher.none.fl_str_mv | MDPI |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation RepairThomas, Kevin KoshyZafar, Mah NoorPitt, William G.Magnesium alloysBiomaterialsBiomedical implantsBiomedical devices made from high-modulus and hardness materials play a critical role in enhancing the quality of life for people with bone-related ailments. While these materials have been successfully used in orthopedic applications, concerns including stress-shielding have necessitated the exploration of alternative solutions. An ideal biomedical implant requires a delicate balance of mechanical performance, corrosion resistance, tissue biocompatibility, and other properties such as tribological performance and osseointegration. This review explores the suitability of biodegradable magnesium (Mg) alloys as a promising material for biomedical implants. It delves into the essential properties of biomedical implants, emphasizing the importance of matching mechanical characteristics with human bone properties to mitigate stress shielding. The corrosion properties of implant materials are discussed, highlighting the need for controlled degradation to ensure the safety and longevity of implants. The focus then shifts to the potential of magnesium alloys as biomedical implants, examining their benefits, limitations, and the challenges associated with their high degradation rates and less-than-satisfactory mechanical properties. Alloying with elements such as aluminum, zinc, and others is explored to improve magnesium alloys’ mechanical performance and corrosion resistance. Furthermore, this review discusses surface modification techniques, including chemical conversion coatings and biomimetic deposition, as effective strategies to enhance the corrosion resistance and biocompatibility of magnesium and its alloys. These modifications offer opportunities to improve the long-term performance of magnesium-based biomedical implants. This review provides a comprehensive overview of the properties, challenges, and potential solutions associated with biodegradable magnesium alloys as a promising material for biomedical implants. It underscores the importance of addressing problems related to mechanical performance, corrosion resistance, and biocompatibility to advance the development of safe and effective biomedical implant materials.Dana Gas Endowed Chair for Chemical EngineeringAmerican University of SharjahSheikh Hamdan Award for Medical SciencesFriends of Cancer Patients (FoCP)MDPI2023-12-20T05:00:00Z2023-12-20T05:00:00Z2023-12-19Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfThomas, K. K., Zafar, M. N., Pitt, W. G., & Husseini, G. A. (2023). Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair. In Applied Sciences (Vol. 14, Issue 1, p. 10). MDPI AG. https://doi.org/10.3390/app140100102076-3417http://hdl.handle.net/11073/2542910.3390/app14010010en_UShttps://doi.org/10.3390/app14010010oai:repository.aus.edu:11073/254292024-08-22T12:04:47Z |
| spellingShingle | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair Thomas, Kevin Koshy Magnesium alloys Biomaterials Biomedical implants |
| status_str | publishedVersion |
| title | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| title_full | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| title_fullStr | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| title_full_unstemmed | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| title_short | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| title_sort | Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair |
| topic | Magnesium alloys Biomaterials Biomedical implants |
| url | http://hdl.handle.net/11073/25429 |