Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis
In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/RAS/PI3K/PTEN genes.
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| Other Authors: | , |
| Format: | article |
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2021
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| Online Access: | http://hdl.handle.net/11073/21487 |
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| _version_ | 1864513444096507904 |
|---|---|
| author | Mukhopadhyay, Debasmita |
| author2 | AlSawaftah, Nour Majdi Husseini, Ghaleb |
| author2_role | author author |
| author_facet | Mukhopadhyay, Debasmita AlSawaftah, Nour Majdi Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | Mukhopadhyay, Debasmita AlSawaftah, Nour Majdi Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2021-05-24T07:17:34Z 2021-05-24T07:17:34Z 2021 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Mukhopadhyay, D., AlSawaftah, N., & Husseini, G. A. (2021). Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis. ACS Pharmacology & Translational Science. https://doi.org/10.1021/acsptsci.1c00040 2575-9108 http://hdl.handle.net/11073/21487 10.1021/acsptsci.1c00040 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | American Chemical Society |
| dc.relation.none.fl_str_mv | https://doi.org/10.1021/acsptsci.1c00040 |
| dc.subject.none.fl_str_mv | SARS-CoV-2 MicroRNA Lung cancer |
| dc.title.none.fl_str_mv | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| dc.type.none.fl_str_mv | Peer-Reviewed Preprint info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/RAS/PI3K/PTEN genes. |
| format | article |
| id | aus_776dc11e193ae9504b812c1cf47eec86 |
| identifier_str_mv | Mukhopadhyay, D., AlSawaftah, N., & Husseini, G. A. (2021). Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis. ACS Pharmacology & Translational Science. https://doi.org/10.1021/acsptsci.1c00040 2575-9108 10.1021/acsptsci.1c00040 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/21487 |
| publishDate | 2021 |
| publisher.none.fl_str_mv | American Chemical Society |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico AnalysisMukhopadhyay, DebasmitaAlSawaftah, Nour MajdiHusseini, GhalebSARS-CoV-2MicroRNALung cancerIn this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/RAS/PI3K/PTEN genes.American Chemical Society2021-05-24T07:17:34Z2021-05-24T07:17:34Z2021Peer-ReviewedPreprintinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMukhopadhyay, D., AlSawaftah, N., & Husseini, G. A. (2021). Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis. ACS Pharmacology & Translational Science. https://doi.org/10.1021/acsptsci.1c000402575-9108http://hdl.handle.net/11073/2148710.1021/acsptsci.1c00040en_UShttps://doi.org/10.1021/acsptsci.1c00040oai:repository.aus.edu:11073/214872024-08-22T12:06:08Z |
| spellingShingle | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis Mukhopadhyay, Debasmita SARS-CoV-2 MicroRNA Lung cancer |
| status_str | publishedVersion |
| title | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| title_full | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| title_fullStr | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| title_full_unstemmed | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| title_short | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| title_sort | Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis |
| topic | SARS-CoV-2 MicroRNA Lung cancer |
| url | http://hdl.handle.net/11073/21487 |