Digital Twins of Biological Systems: A Narrative Review

The concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modelin...

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Main Author: Alsalloum, Ghufran A. (author)
Other Authors: AlSawaftah, Nour Majdi (author), Percival, Kelly M. (author), Husseini, Ghaleb (author)
Format: article
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/11073/25713
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author Alsalloum, Ghufran A.
author2 AlSawaftah, Nour Majdi
Percival, Kelly M.
Husseini, Ghaleb
author2_role author
author
author
author_facet Alsalloum, Ghufran A.
AlSawaftah, Nour Majdi
Percival, Kelly M.
Husseini, Ghaleb
author_role author
dc.creator.none.fl_str_mv Alsalloum, Ghufran A.
AlSawaftah, Nour Majdi
Percival, Kelly M.
Husseini, Ghaleb
dc.date.none.fl_str_mv 2024-11-14T05:59:21Z
2024-11-14T05:59:21Z
2024
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv Alsalloum,G. A.; A Sawaftah,N. M.; Percival K. M. and Husseini,G. A. "Digital Twins of Biological Systems: A Narrative Review," in IEEE Open Journal of Engineering in Medicine and Biology, vol. 5, pp. 670-677, 2024, doi: 10.1109/OJEMB.2024.3426916.
2644-1276
https://hdl.handle.net/11073/25713
10.1109/OJEMB.2024.3426916
dc.language.none.fl_str_mv en_US
dc.publisher.none.fl_str_mv IEEE
dc.relation.none.fl_str_mv https://doi.org/10.1109/OJEMB.2024.3426916
dc.subject.none.fl_str_mv Biological system modeling
Digital twin
Medical technology
dc.title.none.fl_str_mv Digital Twins of Biological Systems: A Narrative Review
dc.type.none.fl_str_mv Peer-Reviewed
Published version
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description The concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modeling, integrating diverse data sources to computationally model dynamic biological systems. This narrative review explores potential DT applications in medicine, from defining DTs and their history to constructing DTs, modeling biologically relevant systems, as well as discussing the benefits, risks, and challenges in their application. The influence of DTs extends beyond healthcare and can revolutionize healthcare management, drug development, clinical trials, and various biomedical research fields.
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identifier_str_mv Alsalloum,G. A.; A Sawaftah,N. M.; Percival K. M. and Husseini,G. A. "Digital Twins of Biological Systems: A Narrative Review," in IEEE Open Journal of Engineering in Medicine and Biology, vol. 5, pp. 670-677, 2024, doi: 10.1109/OJEMB.2024.3426916.
2644-1276
10.1109/OJEMB.2024.3426916
language_invalid_str_mv en_US
network_acronym_str aus
network_name_str aus
oai_identifier_str oai:repository.aus.edu:11073/25713
publishDate 2024
publisher.none.fl_str_mv IEEE
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
spelling Digital Twins of Biological Systems: A Narrative ReviewAlsalloum, Ghufran A.AlSawaftah, Nour MajdiPercival, Kelly M.Husseini, GhalebBiological system modelingDigital twinMedical technologyThe concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modeling, integrating diverse data sources to computationally model dynamic biological systems. This narrative review explores potential DT applications in medicine, from defining DTs and their history to constructing DTs, modeling biologically relevant systems, as well as discussing the benefits, risks, and challenges in their application. The influence of DTs extends beyond healthcare and can revolutionize healthcare management, drug development, clinical trials, and various biomedical research fields.American University of SharjahDana Gas Endowed Chair for Chemical EngineeringSheikh Hamdan Bin Rashid Al Maktoum Award for Medical SciencesFriends of Cancer PatientsIEEE2024-11-14T05:59:21Z2024-11-14T05:59:21Z2024Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfAlsalloum,G. A.; A Sawaftah,N. M.; Percival K. M. and Husseini,G. A. "Digital Twins of Biological Systems: A Narrative Review," in IEEE Open Journal of Engineering in Medicine and Biology, vol. 5, pp. 670-677, 2024, doi: 10.1109/OJEMB.2024.3426916.2644-1276https://hdl.handle.net/11073/2571310.1109/OJEMB.2024.3426916en_UShttps://doi.org/10.1109/OJEMB.2024.3426916oai:repository.aus.edu:11073/257132024-11-14T14:46:55Z
spellingShingle Digital Twins of Biological Systems: A Narrative Review
Alsalloum, Ghufran A.
Biological system modeling
Digital twin
Medical technology
status_str publishedVersion
title Digital Twins of Biological Systems: A Narrative Review
title_full Digital Twins of Biological Systems: A Narrative Review
title_fullStr Digital Twins of Biological Systems: A Narrative Review
title_full_unstemmed Digital Twins of Biological Systems: A Narrative Review
title_short Digital Twins of Biological Systems: A Narrative Review
title_sort Digital Twins of Biological Systems: A Narrative Review
topic Biological system modeling
Digital twin
Medical technology
url https://hdl.handle.net/11073/25713