Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment
The initial uses of ultrasound waves in the medical field were limited to the thermal ablation of solid tumors and as a diagnostic tool. Recent advances at the preclinical stage have allowed the use of ultrasound as a powerful tool to improve drug delivery when the agent is administered encapsulated...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , |
| التنسيق: | article |
| منشور في: |
2017
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://hdl.handle.net/11073/25514 |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513440367771648 |
|---|---|
| author | Salkho, Najla |
| author2 | Turki, Renad Guessoum, O. Martins, Ana M. Vitor, Rute F. Husseini, Ghaleb |
| author2_role | author author author author author |
| author_facet | Salkho, Najla Turki, Renad Guessoum, O. Martins, Ana M. Vitor, Rute F. Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | Salkho, Najla Turki, Renad Guessoum, O. Martins, Ana M. Vitor, Rute F. Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2017 2024-04-18T06:18:12Z 2024-04-18T06:18:12Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Salkho NM, Turki RZ, Guessoum O, Martins AM, Vitor RF, Husseini GA. Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment. Curr Mol Med. 2017;17(10):668-688. doi: 10.2174/1566524018666180416100142. PMID: 29663885. 1566-5240 http://hdl.handle.net/11073/25514 10.2174/1566524018666180416100142 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | Bentham Science |
| dc.relation.none.fl_str_mv | https://doi.org/10.2174/1566524018666180416100142 |
| dc.subject.none.fl_str_mv | Cancer Anti-neoplastic agent Drug delivery Drug Release Liposomes Ultrasound |
| dc.title.none.fl_str_mv | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| dc.type.none.fl_str_mv | Peer-Reviewed Published version info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | The initial uses of ultrasound waves in the medical field were limited to the thermal ablation of solid tumors and as a diagnostic tool. Recent advances at the preclinical stage have allowed the use of ultrasound as a powerful tool to improve drug delivery when the agent is administered encapsulated inside a nanoparticle. This spatial and temporal control of drug release, using a non-invasive modality, is a promising approach to decrease the side effects of conventional chemotherapy in cancer treatments, as it reduces the interaction of the anti-neoplastic agent with healthy tissues. In this review, we explain the physics of ultrasound, introduce and discuss several examples on the use of nanoparticles as drug carriers, with a focus on liposomes. Examples of in vitro and in vivo studies are presented and discussed. |
| format | article |
| id | aus_955ff40c2aa100b509fc6d607dd50f63 |
| identifier_str_mv | Salkho NM, Turki RZ, Guessoum O, Martins AM, Vitor RF, Husseini GA. Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment. Curr Mol Med. 2017;17(10):668-688. doi: 10.2174/1566524018666180416100142. PMID: 29663885. 1566-5240 10.2174/1566524018666180416100142 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/25514 |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Bentham Science |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer TreatmentSalkho, NajlaTurki, RenadGuessoum, O.Martins, Ana M.Vitor, Rute F.Husseini, GhalebCancerAnti-neoplastic agentDrug deliveryDrug ReleaseLiposomesUltrasoundThe initial uses of ultrasound waves in the medical field were limited to the thermal ablation of solid tumors and as a diagnostic tool. Recent advances at the preclinical stage have allowed the use of ultrasound as a powerful tool to improve drug delivery when the agent is administered encapsulated inside a nanoparticle. This spatial and temporal control of drug release, using a non-invasive modality, is a promising approach to decrease the side effects of conventional chemotherapy in cancer treatments, as it reduces the interaction of the anti-neoplastic agent with healthy tissues. In this review, we explain the physics of ultrasound, introduce and discuss several examples on the use of nanoparticles as drug carriers, with a focus on liposomes. Examples of in vitro and in vivo studies are presented and discussed.American University of SharjahBentham Science2024-04-18T06:18:12Z2024-04-18T06:18:12Z2017Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSalkho NM, Turki RZ, Guessoum O, Martins AM, Vitor RF, Husseini GA. Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment. Curr Mol Med. 2017;17(10):668-688. doi: 10.2174/1566524018666180416100142. PMID: 29663885.1566-5240http://hdl.handle.net/11073/2551410.2174/1566524018666180416100142en_UShttps://doi.org/10.2174/1566524018666180416100142oai:repository.aus.edu:11073/255142024-08-22T12:04:41Z |
| spellingShingle | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment Salkho, Najla Cancer Anti-neoplastic agent Drug delivery Drug Release Liposomes Ultrasound |
| status_str | publishedVersion |
| title | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| title_full | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| title_fullStr | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| title_full_unstemmed | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| title_short | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| title_sort | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment |
| topic | Cancer Anti-neoplastic agent Drug delivery Drug Release Liposomes Ultrasound |
| url | http://hdl.handle.net/11073/25514 |