Validation of a Novel Fluorescent Lateral Flow Assay for Rapid Qualitative and Quantitative Assessment of Total Anti-SARS-CoV-2 S-RBD Binding Antibody Units (BAU) from Plasma or Fingerstick Whole-Blood of COVID-19 Vaccinees

Validation of a Novel Fluorescent Lateral Flow Assay for Rapid Qualitative and Quantitative Assessment of Total Anti-SARS-CoV-2 S-RBD Binding Antibody Units (BAU) from Plasma or Fingerstick Whole-Blood of COVID-19 Vaccinees

Background: Limited commercial LFA assays are available to provide a reliable quantitative measurement of the total binding antibody units (BAU/mL) against the receptor-binding domain of the SARS-CoV-2 spike protein (S-RBD). Aim: This study aimed to evaluate the performance of the fluorescence LFA F...

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Bibliographic Details
Main Author: Younes, Nadin (author)
Other Authors: Al-Sadeq, Duaa W. (author), Shurrab, Farah M. (author), Zedan, Hadeel T. (author), Abou-Saleh, Haissam (author), Abo-Halawa, Bushra Y. (author), AlHamaydeh, Fatima M. (author), Elsharafi, Amira E. (author), Daas, Hanin I. (author), Thomas, Swapna (author), Aboalmaaly, Sahar (author), Al Farsi, Afra (author), Al-Buainain, Reeham (author), Ataelmannan, Samar (author), Paul, Jiji (author), Al Saadi, Amana Salih (author), Yassine, Hadi M. (author), Majdalawieh, Amin (author), Ismail, Ahmed (author), Abu-Raddad, Laith J. (author), Nasrallah, Gheyath K. (author)
Format: article
Published: 2022
Subjects:
SARS-CoV-2
COVID-19
serology
Lateral flow assay
Automated immunoassay
CLIA
Neutralizing antibodies
Surrogate virus neutralization test (sVNT)
Online Access:http://hdl.handle.net/11073/25040
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