Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release
Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; e...
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| Other Authors: | , , , |
| Format: | article |
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2018
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| Online Access: | http://hdl.handle.net/11073/21319 |
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| _version_ | 1864513442939928576 |
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| author | Ahmed, Salma E. |
| author2 | Awad, Nahid S. Paul, Vinod Moussa, Hesham Gamal Husseini, Ghaleb |
| author2_role | author author author author |
| author_facet | Ahmed, Salma E. Awad, Nahid S. Paul, Vinod Moussa, Hesham Gamal Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | Ahmed, Salma E. Awad, Nahid S. Paul, Vinod Moussa, Hesham Gamal Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2018 2021-02-02T11:54:48Z 2021-02-02T11:54:48Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Salma E. Ahmed, Nahid Awad, Vinod Paul, Hesham G. Moussa and Ghaleb A. Husseini*, “Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release”, Current Topics in Medicinal Chemistry (2018) 18: 857. https://doi.org/10.2174/1568026618666180608125344 1568-0266 http://hdl.handle.net/11073/21319 10.2174/1568026618666180608125344 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | Bentham Science Publishers |
| dc.relation.none.fl_str_mv | https://doi.org/10.2174/1568026618666180608125344 |
| dc.subject.none.fl_str_mv | Chemotherapy Multi-drug resistance Anthracyclines Doxorubicin Nano-carriers Ultrasound |
| dc.title.none.fl_str_mv | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| dc.type.none.fl_str_mv | Peer-Reviewed Postprint info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; especially when used along with targeting and triggering techniques. This work traces back the history of chemotherapy, addressing the main challenges that have encouraged the medical researchers to seek a sanctuary in nanotechnological-based drug delivery systems that are grafted with appropriate targeting techniques and drug release mechanisms. A special focus will be directed to acoustically triggered liposomes encapsulating doxorubicin. |
| format | article |
| id | aus_aaf82f8c621a80a59e8e00bf7c0d3a13 |
| identifier_str_mv | Salma E. Ahmed, Nahid Awad, Vinod Paul, Hesham G. Moussa and Ghaleb A. Husseini*, “Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release”, Current Topics in Medicinal Chemistry (2018) 18: 857. https://doi.org/10.2174/1568026618666180608125344 1568-0266 10.2174/1568026618666180608125344 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/21319 |
| publishDate | 2018 |
| publisher.none.fl_str_mv | Bentham Science Publishers |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic ReleaseAhmed, Salma E.Awad, Nahid S.Paul, VinodMoussa, Hesham GamalHusseini, GhalebChemotherapyMulti-drug resistanceAnthracyclinesDoxorubicinNano-carriersUltrasoundConventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; especially when used along with targeting and triggering techniques. This work traces back the history of chemotherapy, addressing the main challenges that have encouraged the medical researchers to seek a sanctuary in nanotechnological-based drug delivery systems that are grafted with appropriate targeting techniques and drug release mechanisms. A special focus will be directed to acoustically triggered liposomes encapsulating doxorubicin.Bentham Science Publishers2021-02-02T11:54:48Z2021-02-02T11:54:48Z2018Peer-ReviewedPostprintinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSalma E. Ahmed, Nahid Awad, Vinod Paul, Hesham G. Moussa and Ghaleb A. Husseini*, “Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release”, Current Topics in Medicinal Chemistry (2018) 18: 857. https://doi.org/10.2174/15680266186661806081253441568-0266http://hdl.handle.net/11073/2131910.2174/1568026618666180608125344en_UShttps://doi.org/10.2174/1568026618666180608125344oai:repository.aus.edu:11073/213192024-08-22T12:05:42Z |
| spellingShingle | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release Ahmed, Salma E. Chemotherapy Multi-drug resistance Anthracyclines Doxorubicin Nano-carriers Ultrasound |
| status_str | publishedVersion |
| title | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| title_full | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| title_fullStr | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| title_full_unstemmed | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| title_short | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| title_sort | Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release |
| topic | Chemotherapy Multi-drug resistance Anthracyclines Doxorubicin Nano-carriers Ultrasound |
| url | http://hdl.handle.net/11073/21319 |