Nanoparticle-based materials in anticancer drug delivery: Current and future prospects
The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these drugs can lead to undesirable side effects on healthy cells. To overcome thi...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , |
| Format: | article |
| Published: |
2023
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11073/25502 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513442123087872 |
|---|---|
| author | Ajith, Saniha Aysha |
| author2 | Almomani, Fares Elhissi, Abdelbary Husseini, Ghaleb |
| author2_role | author author author |
| author_facet | Ajith, Saniha Aysha Almomani, Fares Elhissi, Abdelbary Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | Ajith, Saniha Aysha Almomani, Fares Elhissi, Abdelbary Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2023 2024-03-21T07:31:14Z 2024-03-21T07:31:14Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Saniha Ajith, Fares Almomani, Abdelbary Elhissi, Ghaleb A. Husseini, Nanoparticle-based materials in anticancer drug delivery: Current and future prospects, Heliyon, Volume 9, Issue 11, 2023, e21227, ISSN 2405-8440, https://doi.org/10.1016/j.heliyon.2023.e21227. 2405-8440 http://hdl.handle.net/11073/25502 10.1016/j.heliyon.2023.e21227 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.relation.none.fl_str_mv | https://doi.org/10.1016/j.heliyon.2023.e21227 |
| dc.subject.none.fl_str_mv | Drug delivery Nanomaterials Cancer therapy Nanocarriers Nanomedicine |
| dc.title.none.fl_str_mv | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| dc.type.none.fl_str_mv | Peer-Reviewed Published version info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these drugs can lead to undesirable side effects on healthy cells. To overcome this challenge and improve cancer cell targeting, many novel nanocarriers have been developed to deliver drugs directly to the cancerous cells and minimize effects on the healthy tissues. The majority of the research studies conclude that using drugs encapsulated in nanocarriers is a much safer and more effective alternative than delivering the drug alone in its free form. This review provides a summary of the types of nanocarriers mainly studied for cancer drug delivery, namely: liposomes, polymeric micelles, dendrimers, magnetic nanoparticles, mesoporous nanoparticles, gold nanoparticles, carbon nanotubes and quantum dots. In this review, the synthesis, applications, advantages, disadvantages, and previous studies of these nanomaterials are discussed in detail. Furthermore, the future opportunities and possible challenges of translating these materials into clinical applications are also reported. |
| format | article |
| id | aus_ac233f9afd5a192aba39a2c9d74b6e26 |
| identifier_str_mv | Saniha Ajith, Fares Almomani, Abdelbary Elhissi, Ghaleb A. Husseini, Nanoparticle-based materials in anticancer drug delivery: Current and future prospects, Heliyon, Volume 9, Issue 11, 2023, e21227, ISSN 2405-8440, https://doi.org/10.1016/j.heliyon.2023.e21227. 2405-8440 10.1016/j.heliyon.2023.e21227 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/25502 |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Elsevier |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Nanoparticle-based materials in anticancer drug delivery: Current and future prospectsAjith, Saniha AyshaAlmomani, FaresElhissi, AbdelbaryHusseini, GhalebDrug deliveryNanomaterialsCancer therapyNanocarriersNanomedicineThe past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these drugs can lead to undesirable side effects on healthy cells. To overcome this challenge and improve cancer cell targeting, many novel nanocarriers have been developed to deliver drugs directly to the cancerous cells and minimize effects on the healthy tissues. The majority of the research studies conclude that using drugs encapsulated in nanocarriers is a much safer and more effective alternative than delivering the drug alone in its free form. This review provides a summary of the types of nanocarriers mainly studied for cancer drug delivery, namely: liposomes, polymeric micelles, dendrimers, magnetic nanoparticles, mesoporous nanoparticles, gold nanoparticles, carbon nanotubes and quantum dots. In this review, the synthesis, applications, advantages, disadvantages, and previous studies of these nanomaterials are discussed in detail. Furthermore, the future opportunities and possible challenges of translating these materials into clinical applications are also reported.Qatar National LibraryElsevier2024-03-21T07:31:14Z2024-03-21T07:31:14Z2023Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSaniha Ajith, Fares Almomani, Abdelbary Elhissi, Ghaleb A. Husseini, Nanoparticle-based materials in anticancer drug delivery: Current and future prospects, Heliyon, Volume 9, Issue 11, 2023, e21227, ISSN 2405-8440, https://doi.org/10.1016/j.heliyon.2023.e21227.2405-8440http://hdl.handle.net/11073/2550210.1016/j.heliyon.2023.e21227en_UShttps://doi.org/10.1016/j.heliyon.2023.e21227oai:repository.aus.edu:11073/255022024-08-22T12:05:18Z |
| spellingShingle | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects Ajith, Saniha Aysha Drug delivery Nanomaterials Cancer therapy Nanocarriers Nanomedicine |
| status_str | publishedVersion |
| title | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| title_full | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| title_fullStr | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| title_full_unstemmed | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| title_short | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| title_sort | Nanoparticle-based materials in anticancer drug delivery: Current and future prospects |
| topic | Drug delivery Nanomaterials Cancer therapy Nanocarriers Nanomedicine |
| url | http://hdl.handle.net/11073/25502 |