Fluoroscopic 3D Images Generation Using A GAN Method

A Master of Science thesis in Biomedical Engineering by Mohammad Nabeel Mohammad Alshrbaji entitled, “Fluoroscopic 3D Images Generation Using A GAN Method”, submitted in December 2022. Thesis advisor is Dr. Salam Dhou. Soft copy is available (Thesis, Completion Certificate, Approval Signatures, and...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Alshrbaji, Mohammad Nabeel Mohammad (author)
التنسيق: doctoralThesis
منشور في: 2022
الموضوعات:
الوصول للمادة أونلاين:http://hdl.handle.net/11073/25164
الوسوم: إضافة وسم
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author Alshrbaji, Mohammad Nabeel Mohammad
author_facet Alshrbaji, Mohammad Nabeel Mohammad
author_role author
dc.contributor.none.fl_str_mv Dhou, Salam
dc.creator.none.fl_str_mv Alshrbaji, Mohammad Nabeel Mohammad
dc.date.none.fl_str_mv 2022-12
2023-02-28T09:25:27Z
2023-02-28T09:25:27Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv 35.232-2022.46
http://hdl.handle.net/11073/25164
dc.language.none.fl_str_mv en_US
dc.subject.none.fl_str_mv Radiotherapy
CBCT
Cone Beam Computed Tomography (CBCT)
GAN
Generative Adversarial Network (GAN)
3D Fluoroscopy
Respiratory Motion
dc.title.none.fl_str_mv Fluoroscopic 3D Images Generation Using A GAN Method
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/doctoralThesis
description A Master of Science thesis in Biomedical Engineering by Mohammad Nabeel Mohammad Alshrbaji entitled, “Fluoroscopic 3D Images Generation Using A GAN Method”, submitted in December 2022. Thesis advisor is Dr. Salam Dhou. Soft copy is available (Thesis, Completion Certificate, Approval Signatures, and AUS Archives Consent Form).
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network_acronym_str aus
network_name_str aus
oai_identifier_str oai:repository.aus.edu:11073/25164
publishDate 2022
repository.mail.fl_str_mv
repository.name.fl_str_mv
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spelling Fluoroscopic 3D Images Generation Using A GAN MethodAlshrbaji, Mohammad Nabeel MohammadRadiotherapyCBCTCone Beam Computed Tomography (CBCT)GANGenerative Adversarial Network (GAN)3D FluoroscopyRespiratory MotionA Master of Science thesis in Biomedical Engineering by Mohammad Nabeel Mohammad Alshrbaji entitled, “Fluoroscopic 3D Images Generation Using A GAN Method”, submitted in December 2022. Thesis advisor is Dr. Salam Dhou. Soft copy is available (Thesis, Completion Certificate, Approval Signatures, and AUS Archives Consent Form).Respiratory motion is a major source of error in radiation therapy for thorax and lung cancer. Image-Guided Radiation Therapy (IGRT) is the use of frequent imaging during radiation therapy to enhance the precision and accuracy of the treatment delivery. Cone Beam Computed Tomography (CBCT) is an imaging modality that is used in radiotherapy delivery rooms to account for respiratory motion uncertainties. One CBCT scan results in a set of projections (2D images), which is taken in a couple of minutes while the patient is normally breathing. The known procedure for utilizing these projections is to sort them into breathing phases and reconstruct a 3D image from each, which results in making 4D-CBCT images. These 4D-CBCT images are used to estimate fluoroscopic images right before the treatment delivery. The objective of this work is to generate 3D fluoroscopic images of the lungs from two orthogonal projections using a Generative Adversarial Network (GAN) method. GAN is a powerful deep learning-based technique that allows two independent models to develop and compete with each other, which are named the generator (G) and the discriminator (D). This method has the potential of generating a 3D volume image representing patient anatomy at the time of treatment delivery from any two orthogonal projections. Using multiple pairs of projections from multiple pairs of angles, the model can generate a 3D fluoroscopic image representing the respiratory motion while the patient is in the treatment position. The resulting generated 3D images give very good results in terms of generating quality images representing the same breathing phase as the orthogonal projections. The quantitative results include the measures of Peak Signal-to-Noise Ratio (PSNR) and Structural Similarity Index (SSIM), which equal 26.01 and 0.572, respectively. Although the proposed method does not intend to replace the used motion model-based methods, its goal is to add niche applications in radiation therapy, such as tumor tracking and dose verification.College of EngineeringMultidisciplinary ProgramsMaster of Science in Biomedical Engineering (MSBME)Dhou, Salam2023-02-28T09:25:27Z2023-02-28T09:25:27Z2022-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdf35.232-2022.46http://hdl.handle.net/11073/25164en_USoai:repository.aus.edu:11073/251642025-06-26T12:27:27Z
spellingShingle Fluoroscopic 3D Images Generation Using A GAN Method
Alshrbaji, Mohammad Nabeel Mohammad
Radiotherapy
CBCT
Cone Beam Computed Tomography (CBCT)
GAN
Generative Adversarial Network (GAN)
3D Fluoroscopy
Respiratory Motion
status_str publishedVersion
title Fluoroscopic 3D Images Generation Using A GAN Method
title_full Fluoroscopic 3D Images Generation Using A GAN Method
title_fullStr Fluoroscopic 3D Images Generation Using A GAN Method
title_full_unstemmed Fluoroscopic 3D Images Generation Using A GAN Method
title_short Fluoroscopic 3D Images Generation Using A GAN Method
title_sort Fluoroscopic 3D Images Generation Using A GAN Method
topic Radiotherapy
CBCT
Cone Beam Computed Tomography (CBCT)
GAN
Generative Adversarial Network (GAN)
3D Fluoroscopy
Respiratory Motion
url http://hdl.handle.net/11073/25164