Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
This study focuses on the development of antimicrobial fibres for use in medical and healthcare textile industries. Carbon dots (CDs) were designed with boronic acid groups for the attachment to cellulose fibres found in cotton textiles and to enhance their attachment to glycogens on bacterial surfa...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , |
| Format: | article |
| Published: |
2024
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11073/25513 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513442917908480 |
|---|---|
| author | Radha, Remya |
| author2 | Makhlouf, Zinb Diab, Rasha Al-Sayah, Mohammad |
| author2_role | author author author |
| author_facet | Radha, Remya Makhlouf, Zinb Diab, Rasha Al-Sayah, Mohammad |
| author_role | author |
| dc.creator.none.fl_str_mv | Radha, Remya Makhlouf, Zinb Diab, Rasha Al-Sayah, Mohammad |
| dc.date.none.fl_str_mv | 2024-04-18T05:24:55Z 2024-04-18T05:24:55Z 2024-04-17 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Radha R, Makhlouf Z, Diab R, Al-Sayah MH. 2024. Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres. R. Soc. Open Sci. 11: 231755. https://doi.org/10.1098/rsos.231755 2054-5703 http://hdl.handle.net/11073/25513 10.1098/rsos.231755 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | Royal Society |
| dc.relation.none.fl_str_mv | https://doi.org/10.1098/rsos.231755 |
| dc.subject.none.fl_str_mv | Carbon dots Cellulose Boronic acid Curcumin Antimicrobial fibres Staphylococcus epidermidis |
| dc.title.none.fl_str_mv | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| dc.type.none.fl_str_mv | Peer-Reviewed Published version info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | This study focuses on the development of antimicrobial fibres for use in medical and healthcare textile industries. Carbon dots (CDs) were designed with boronic acid groups for the attachment to cellulose fibres found in cotton textiles and to enhance their attachment to glycogens on bacterial surfaces. Boronic acid-based and curcumin-based CDs were prepared and characterized using various techniques, showing a nanoscale size and zeta potential values. The CDs inhibited the growth of both Staphylococcus epidermidis and Escherichia coli bacteria, with UV-activated CDs demonstrating improved antibacterial activity. The antimicrobial activity of the CDs was then tested, revealing strong adherence to cellulose paper fibres with no CD diffusion and potent inhibition of bacterial growth. Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. However, CD-modified cellulose paper fibres showed no toxicity against human cell lines, highlighting the antimicrobial properties of the CD-modified cellulose fibres are safe for human use. These findings show promising potential for applications in both industrial and clinical settings. |
| format | article |
| id | aus_be07cd8f39de6a0d76ba9606f8a7e286 |
| identifier_str_mv | Radha R, Makhlouf Z, Diab R, Al-Sayah MH. 2024. Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres. R. Soc. Open Sci. 11: 231755. https://doi.org/10.1098/rsos.231755 2054-5703 10.1098/rsos.231755 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/25513 |
| publishDate | 2024 |
| publisher.none.fl_str_mv | Royal Society |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibresRadha, RemyaMakhlouf, ZinbDiab, RashaAl-Sayah, MohammadCarbon dotsCelluloseBoronic acidCurcuminAntimicrobial fibresStaphylococcus epidermidisThis study focuses on the development of antimicrobial fibres for use in medical and healthcare textile industries. Carbon dots (CDs) were designed with boronic acid groups for the attachment to cellulose fibres found in cotton textiles and to enhance their attachment to glycogens on bacterial surfaces. Boronic acid-based and curcumin-based CDs were prepared and characterized using various techniques, showing a nanoscale size and zeta potential values. The CDs inhibited the growth of both Staphylococcus epidermidis and Escherichia coli bacteria, with UV-activated CDs demonstrating improved antibacterial activity. The antimicrobial activity of the CDs was then tested, revealing strong adherence to cellulose paper fibres with no CD diffusion and potent inhibition of bacterial growth. Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. However, CD-modified cellulose paper fibres showed no toxicity against human cell lines, highlighting the antimicrobial properties of the CD-modified cellulose fibres are safe for human use. These findings show promising potential for applications in both industrial and clinical settings.American University of SharjahRoyal Society2024-04-18T05:24:55Z2024-04-18T05:24:55Z2024-04-17Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfRadha R, Makhlouf Z, Diab R, Al-Sayah MH. 2024. Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres. R. Soc. Open Sci. 11: 231755. https://doi.org/10.1098/rsos.2317552054-5703http://hdl.handle.net/11073/2551310.1098/rsos.231755en_UShttps://doi.org/10.1098/rsos.231755oai:repository.aus.edu:11073/255132024-08-22T12:00:14Z |
| spellingShingle | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres Radha, Remya Carbon dots Cellulose Boronic acid Curcumin Antimicrobial fibres Staphylococcus epidermidis |
| status_str | publishedVersion |
| title | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| title_full | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| title_fullStr | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| title_full_unstemmed | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| title_short | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| title_sort | Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres |
| topic | Carbon dots Cellulose Boronic acid Curcumin Antimicrobial fibres Staphylococcus epidermidis |
| url | http://hdl.handle.net/11073/25513 |