Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature demonstrates that ultrasound has potential in other medical applications, i...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| التنسيق: | article |
| منشور في: |
2020
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://hdl.handle.net/11073/19723 |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513443784032256 |
|---|---|
| author | AlSawaftah, Nour Majdi |
| author2 | Husseini, Ghaleb |
| author2_role | author |
| author_facet | AlSawaftah, Nour Majdi Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | AlSawaftah, Nour Majdi Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2020-08-19T06:29:28Z 2020-08-19T06:29:28Z 2020 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Al Sawaftah, N. M. & Hussaini, G. A. (2020). Ultrasound-mediated drug delivery in cancer therapy: a review. Journal of Nanoscience and Nanotechnology, 20(12), 7211-7230. doi: doi.org/10.1166/jnn.2020.18877 1533-4899 http://hdl.handle.net/11073/19723 10.1166/jnn.2020.18877 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | American Scientific Publishers |
| dc.relation.none.fl_str_mv | https://doi.org/10.1166/jnn.2020.18877 |
| dc.subject.none.fl_str_mv | Ultrasound Micelle Liposome Targeted delivery Cavitation |
| dc.title.none.fl_str_mv | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| dc.type.none.fl_str_mv | Postprint Peer-Reviewed info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature demonstrates that ultrasound has potential in other medical applications, including targeted drug delivery. Site-specific drug delivery involves delivering drugs to diseased areas with a high degree of precision, which is particularly advantageous in cancer treatment as it would minimize the adverse side effects experienced by patients. This review addresses the ability of ultrasound to induce localized and controlled drug release from nanocarriers, namely micelles and liposomes, utilizing thermal and/or mechanical effects. The interactions of ultrasound with micelles and liposomes, the effects of the lipid composition, and ultrasound parameters on the release of encapsulated drugs are discussed. In addition, a survey of the literature detailing some in vitro and in vivo ultrasound triggered drug delivery systems is presented. |
| format | article |
| id | aus_c346371b32d2a257c1a64d06b1e9f4c2 |
| identifier_str_mv | Al Sawaftah, N. M. & Hussaini, G. A. (2020). Ultrasound-mediated drug delivery in cancer therapy: a review. Journal of Nanoscience and Nanotechnology, 20(12), 7211-7230. doi: doi.org/10.1166/jnn.2020.18877 1533-4899 10.1166/jnn.2020.18877 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/19723 |
| publishDate | 2020 |
| publisher.none.fl_str_mv | American Scientific Publishers |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A ReviewAlSawaftah, Nour MajdiHusseini, GhalebUltrasoundMicelleLiposomeTargeted deliveryCavitationThe use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature demonstrates that ultrasound has potential in other medical applications, including targeted drug delivery. Site-specific drug delivery involves delivering drugs to diseased areas with a high degree of precision, which is particularly advantageous in cancer treatment as it would minimize the adverse side effects experienced by patients. This review addresses the ability of ultrasound to induce localized and controlled drug release from nanocarriers, namely micelles and liposomes, utilizing thermal and/or mechanical effects. The interactions of ultrasound with micelles and liposomes, the effects of the lipid composition, and ultrasound parameters on the release of encapsulated drugs are discussed. In addition, a survey of the literature detailing some in vitro and in vivo ultrasound triggered drug delivery systems is presented.American Scientific Publishers2020-08-19T06:29:28Z2020-08-19T06:29:28Z2020PostprintPeer-Reviewedinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfAl Sawaftah, N. M. & Hussaini, G. A. (2020). Ultrasound-mediated drug delivery in cancer therapy: a review. Journal of Nanoscience and Nanotechnology, 20(12), 7211-7230. doi: doi.org/10.1166/jnn.2020.188771533-4899http://hdl.handle.net/11073/1972310.1166/jnn.2020.18877en_UShttps://doi.org/10.1166/jnn.2020.18877oai:repository.aus.edu:11073/197232024-08-22T12:06:04Z |
| spellingShingle | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review AlSawaftah, Nour Majdi Ultrasound Micelle Liposome Targeted delivery Cavitation |
| status_str | publishedVersion |
| title | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| title_full | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| title_fullStr | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| title_full_unstemmed | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| title_short | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| title_sort | Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review |
| topic | Ultrasound Micelle Liposome Targeted delivery Cavitation |
| url | http://hdl.handle.net/11073/19723 |