Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment
Ultrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. Cancer-targeted drug delivery involves delivering chemotherapeutic drugs to tumor s...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , |
| التنسيق: | article |
| منشور في: |
2023
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://hdl.handle.net/11073/25300 |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513438907105280 |
|---|---|
| author | Almajed, Zeyad Mohamed |
| author2 | AlSawaftah, Nour Majdi Sulieman, Hana Husseini, Ghaleb |
| author2_role | author author author |
| author_facet | Almajed, Zeyad Mohamed AlSawaftah, Nour Majdi Sulieman, Hana Husseini, Ghaleb |
| author_role | author |
| dc.creator.none.fl_str_mv | Almajed, Zeyad Mohamed AlSawaftah, Nour Majdi Sulieman, Hana Husseini, Ghaleb |
| dc.date.none.fl_str_mv | 2023-08-25T09:05:43Z 2023-08-25T09:05:43Z 2023-07 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Almajed, Z., Al Sawaftah, N. M., Sulieman, H., & Husseini, G. A. (2023). Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment. In Journal of Biomedical Nanotechnology (Vol. 19, Issue 7, pp. 1128–1140). American Scientific Publishers. https://doi.org/10.1166/jbn.2023.3617 1550-7033 http://hdl.handle.net/11073/25300 10.1166/jbn.2023.3617 |
| dc.language.none.fl_str_mv | en_US |
| dc.publisher.none.fl_str_mv | American Scientific Publishers |
| dc.relation.none.fl_str_mv | https://doi.org/10.1166/jbn.2023.3617 |
| dc.subject.none.fl_str_mv | Ultrasound Cavitation Liposome Targeted delivery Contrast agent Theranostic |
| dc.title.none.fl_str_mv | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| dc.type.none.fl_str_mv | Peer-Reviewed Published version info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Ultrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. Cancer-targeted drug delivery involves delivering chemotherapeutic drugs to tumor sites with a high degree of precision, which would minimize the adverse side effects experienced by patients. Several nanocarriers have been studied as possible nanocarriers; however, liposomes stood out from the rest because of their non-immunogenicity, amphiphilic nature, ease of functionalization, and stimuli-responsiveness. This review addresses the role of US in the synthesis of liposomes, its ability to induce localized and controlled drug release from liposomes, as well as the integration of US-induced release and US-imaging using liposomes as contrast agents utilizing thermal and/or mechanical effects. |
| format | article |
| id | aus_d45b4dc32f58cc37f7987b9b1493e263 |
| identifier_str_mv | Almajed, Z., Al Sawaftah, N. M., Sulieman, H., & Husseini, G. A. (2023). Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment. In Journal of Biomedical Nanotechnology (Vol. 19, Issue 7, pp. 1128–1140). American Scientific Publishers. https://doi.org/10.1166/jbn.2023.3617 1550-7033 10.1166/jbn.2023.3617 |
| language_invalid_str_mv | en_US |
| network_acronym_str | aus |
| network_name_str | aus |
| oai_identifier_str | oai:repository.aus.edu:11073/25300 |
| publishDate | 2023 |
| publisher.none.fl_str_mv | American Scientific Publishers |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer TreatmentAlmajed, Zeyad MohamedAlSawaftah, Nour MajdiSulieman, HanaHusseini, GhalebUltrasoundCavitationLiposomeTargeted deliveryContrast agentTheranosticUltrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. Cancer-targeted drug delivery involves delivering chemotherapeutic drugs to tumor sites with a high degree of precision, which would minimize the adverse side effects experienced by patients. Several nanocarriers have been studied as possible nanocarriers; however, liposomes stood out from the rest because of their non-immunogenicity, amphiphilic nature, ease of functionalization, and stimuli-responsiveness. This review addresses the role of US in the synthesis of liposomes, its ability to induce localized and controlled drug release from liposomes, as well as the integration of US-induced release and US-imaging using liposomes as contrast agents utilizing thermal and/or mechanical effects.American University of SharjahAl-Jalila FoundationAl Qasimi FoundationPatient's Friends Committee of SharjahBiosciences and Bioengineering Research InstituteGCC Co-Fund ProgramTakamul programTechnology Innovation Pioneer (TIP) Healthcare AwardsSheikh Hamdan Award for Medical SciencesFriends of Cancer Patients (FoCP)Dana Gas Endowed Chair for Chemical EngineeringAmerican Scientific Publishers2023-08-25T09:05:43Z2023-08-25T09:05:43Z2023-07Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfAlmajed, Z., Al Sawaftah, N. M., Sulieman, H., & Husseini, G. A. (2023). Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment. In Journal of Biomedical Nanotechnology (Vol. 19, Issue 7, pp. 1128–1140). American Scientific Publishers. https://doi.org/10.1166/jbn.2023.36171550-7033http://hdl.handle.net/11073/2530010.1166/jbn.2023.3617en_UShttps://doi.org/10.1166/jbn.2023.3617oai:repository.aus.edu:11073/253002024-08-22T12:04:08Z |
| spellingShingle | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment Almajed, Zeyad Mohamed Ultrasound Cavitation Liposome Targeted delivery Contrast agent Theranostic |
| status_str | publishedVersion |
| title | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| title_full | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| title_fullStr | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| title_full_unstemmed | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| title_short | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| title_sort | Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment |
| topic | Ultrasound Cavitation Liposome Targeted delivery Contrast agent Theranostic |
| url | http://hdl.handle.net/11073/25300 |