Design and Characterization of Flexible and Implantable Electrodes

A Master of Science thesis in Biomedical Engineering by Aseel Dirar Alatoom entitled, “Design and Characterization of Flexible and Implantable Electrodes”, submitted in April 2019. Thesis advisor is Dr. Amani Al-Othman and thesis co-advisors are Dr. Hasan Awad Moh'd Al-Nashash and Dr. Mohammad...

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Main Author: Alatoom, Aseel Dirar (author)
Format: doctoralThesis
Published: 2019
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Online Access:http://hdl.handle.net/11073/16482
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author Alatoom, Aseel Dirar
author_facet Alatoom, Aseel Dirar
author_role author
dc.contributor.none.fl_str_mv Al-Othman, Amani
Al Nashash, Hasan
Al-Sayah, Mohammad Hussein
dc.creator.none.fl_str_mv Alatoom, Aseel Dirar
dc.date.none.fl_str_mv 2019-09-03T09:21:06Z
2019-09-03T09:21:06Z
2019-04
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv 35.232-2019.36
http://hdl.handle.net/11073/16482
dc.language.none.fl_str_mv en_US
dc.subject.none.fl_str_mv Implantable electrodes
Conductive polymers
Electrochemical impedance spectroscopy
Silicone-titanium dioxide
Silicone-stainless steel
Neuroprostheses
dc.title.none.fl_str_mv Design and Characterization of Flexible and Implantable Electrodes
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/doctoralThesis
description A Master of Science thesis in Biomedical Engineering by Aseel Dirar Alatoom entitled, “Design and Characterization of Flexible and Implantable Electrodes”, submitted in April 2019. Thesis advisor is Dr. Amani Al-Othman and thesis co-advisors are Dr. Hasan Awad Moh'd Al-Nashash and Dr. Mohammad Hussein Al-Sayah. Soft and hard copy available.
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network_acronym_str aus
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oai_identifier_str oai:repository.aus.edu:11073/16482
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spelling Design and Characterization of Flexible and Implantable ElectrodesAlatoom, Aseel DirarImplantable electrodesConductive polymersElectrochemical impedance spectroscopySilicone-titanium dioxideSilicone-stainless steelNeuroprosthesesA Master of Science thesis in Biomedical Engineering by Aseel Dirar Alatoom entitled, “Design and Characterization of Flexible and Implantable Electrodes”, submitted in April 2019. Thesis advisor is Dr. Amani Al-Othman and thesis co-advisors are Dr. Hasan Awad Moh'd Al-Nashash and Dr. Mohammad Hussein Al-Sayah. Soft and hard copy available.Implantable bioelectrodes have the potential to advance neural sensing and muscle stimulation, especially in cases of peripheral nerve injuries. In such cases, the application of electrical stimulation to the muscles prevents muscular atrophy and helps to bridge the gap between the injured nerve and the corresponding muscle. Conventional materials for these implantable electrodes are usually metals, but they suffer from several limitations ranging from mechanical mismatch to immunological responses. Another problem is damage to tissues due to mechanical forces exerted on soft tissues by the stiff mechanical electrodes. Therefore, there is a need for the development of flexible, durable implantable electrodes with low interfacial impedance characteristics. This thesis discusses the fabrication and characterization of novel, low-cost, flexible bioelectrodes based on silicone polymer (polysiloxane) and other electrode materials, including titanium dioxide and stainless steel powder as well as their combinations. For this purpose, this work synthesized and characterized three types of implantable electrodes based on their electrochemical and mechanical properties; where titanium dioxide, stainless steel, and a mixture of the two were used as the main conducting components for fabrication. The titanium dioxide-based samples exhibited a bulk impedance of 353±13.5 Ω with an impedance of 198±183 kΩ at frequency of 1 kHz; in addition, they had a modulus of elasticity of 4.52±1.15 MPa. The stainless steel-based electrodes had a bulk impedance of 1.69±1.16 kΩ and an impedance of 1.21±1.13 MΩ at frequency of 1 kHz, and they had a modulus of elasticity of 0.722±0.393 MPa. The third type, which was a mixture of both titanium dioxide and stainless steel-based samples, had a bulk impedance of 1.71±0.849 kΩ and an impedance of 191 ± 160 kΩ at frequency of 1 kHz; along with a modulus of elasticity of 0.453±0.32 MPa. The results for the silicone with metal powders showed promising electrochemical and mechanical characteristics with flexible and ductile properties, with the titanium dioxide-based material performing the best. Compared with the values reported in the literature, the results show superior performance. Thus, supporting the composite material’s potential for being used in implantable electrode applications.College of EngineeringMultidisciplinary ProgramsMaster of Science in Biomedical Engineering (MSBME)Al-Othman, AmaniAl Nashash, HasanAl-Sayah, Mohammad Hussein2019-09-03T09:21:06Z2019-09-03T09:21:06Z2019-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdf35.232-2019.36http://hdl.handle.net/11073/16482en_USoai:repository.aus.edu:11073/164822025-06-26T12:22:20Z
spellingShingle Design and Characterization of Flexible and Implantable Electrodes
Alatoom, Aseel Dirar
Implantable electrodes
Conductive polymers
Electrochemical impedance spectroscopy
Silicone-titanium dioxide
Silicone-stainless steel
Neuroprostheses
status_str publishedVersion
title Design and Characterization of Flexible and Implantable Electrodes
title_full Design and Characterization of Flexible and Implantable Electrodes
title_fullStr Design and Characterization of Flexible and Implantable Electrodes
title_full_unstemmed Design and Characterization of Flexible and Implantable Electrodes
title_short Design and Characterization of Flexible and Implantable Electrodes
title_sort Design and Characterization of Flexible and Implantable Electrodes
topic Implantable electrodes
Conductive polymers
Electrochemical impedance spectroscopy
Silicone-titanium dioxide
Silicone-stainless steel
Neuroprostheses
url http://hdl.handle.net/11073/16482