The Emerging Role of MXenes in Cancer Treatment

MXenes are relatively new 2D materials made up of carbides and/or nitrides of transition metals with a chemical formula Mn+1XnTx. They are usually fabricated by chemically etching a ceramic phase. MXenes possess tunable catalytic, optical, and electronic properties, which have attracted significant...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Salkho, Najla (author)
مؤلفون آخرون: Pitt, William (author), Husseini, Ghaleb (author)
التنسيق: article
منشور في: 2025
الموضوعات:
الوصول للمادة أونلاين:https://hdl.handle.net/11073/33244
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author Salkho, Najla
author2 Pitt, William
Husseini, Ghaleb
author2_role author
author
author_facet Salkho, Najla
Pitt, William
Husseini, Ghaleb
author_role author
dc.creator.none.fl_str_mv Salkho, Najla
Pitt, William
Husseini, Ghaleb
dc.date.none.fl_str_mv 2025
2026-03-10T09:01:11Z
2026-03-10T09:01:11Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv Salkho, N.M.; Pitt, W.G.; Husseini, G.A. The Emerging Role of MXenes in Cancer Treatment. Int. J. Mol. Sci. 2025, 26, 10296. https://doi.org/10.3390/ijms262110296
1422-0067
https://hdl.handle.net/11073/33244
10.3390/ijms262110296
dc.language.none.fl_str_mv en_US
dc.relation.none.fl_str_mv https://doi.org/10.3390/ijms262110296
dc.subject.none.fl_str_mv MXenes
2D nanomaterials
Photothermal therapy
Cancer treatment
Biocompatibility
dc.title.none.fl_str_mv The Emerging Role of MXenes in Cancer Treatment
dc.type.none.fl_str_mv Peer-Reviewed
Published version
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description MXenes are relatively new 2D materials made up of carbides and/or nitrides of transition metals with a chemical formula Mn+1XnTx. They are usually fabricated by chemically etching a ceramic phase. MXenes possess tunable catalytic, optical, and electronic properties, which have attracted significant research interest, primarily in energy storage and biosensing applications. Since their first fabrication in 2011, there has been a rapid increase in studies investigating the use of MXenes in a wide range of applications. In this review, the synthesis methods of MXenes are discussed. Then, the potential application of MXenes in cancer treatment is highlighted based on current research. The ability of MXene to convert light, usually NIR (I and II), to heat with improved conversion efficiencies makes it a competitive candidate for photothermal cancer therapy. Moreover, the surface of MXenes can be modified with drugs or nanoparticles, thereby achieving synergistic photo/chemo/, and sonodynamic therapy. This review also examines the available research on the biocompatibility and cytotoxicity of MXenes.
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identifier_str_mv Salkho, N.M.; Pitt, W.G.; Husseini, G.A. The Emerging Role of MXenes in Cancer Treatment. Int. J. Mol. Sci. 2025, 26, 10296. https://doi.org/10.3390/ijms262110296
1422-0067
10.3390/ijms262110296
language_invalid_str_mv en_US
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spelling The Emerging Role of MXenes in Cancer TreatmentSalkho, NajlaPitt, WilliamHusseini, GhalebMXenes2D nanomaterialsPhotothermal therapyCancer treatmentBiocompatibilityMXenes are relatively new 2D materials made up of carbides and/or nitrides of transition metals with a chemical formula Mn+1XnTx. They are usually fabricated by chemically etching a ceramic phase. MXenes possess tunable catalytic, optical, and electronic properties, which have attracted significant research interest, primarily in energy storage and biosensing applications. Since their first fabrication in 2011, there has been a rapid increase in studies investigating the use of MXenes in a wide range of applications. In this review, the synthesis methods of MXenes are discussed. Then, the potential application of MXenes in cancer treatment is highlighted based on current research. The ability of MXene to convert light, usually NIR (I and II), to heat with improved conversion efficiencies makes it a competitive candidate for photothermal cancer therapy. Moreover, the surface of MXenes can be modified with drugs or nanoparticles, thereby achieving synergistic photo/chemo/, and sonodynamic therapy. This review also examines the available research on the biocompatibility and cytotoxicity of MXenes.American University of SharjahSheikh Hamdan Award for Medical SciencesFriends of Cancer Patients (FoCP)2026-03-10T09:01:11Z2026-03-10T09:01:11Z2025Peer-ReviewedPublished versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSalkho, N.M.; Pitt, W.G.; Husseini, G.A. The Emerging Role of MXenes in Cancer Treatment. Int. J. Mol. Sci. 2025, 26, 10296. https://doi.org/10.3390/ijms2621102961422-0067https://hdl.handle.net/11073/3324410.3390/ijms262110296en_UShttps://doi.org/10.3390/ijms262110296oai:repository.aus.edu:11073/332442026-03-11T05:23:47Z
spellingShingle The Emerging Role of MXenes in Cancer Treatment
Salkho, Najla
MXenes
2D nanomaterials
Photothermal therapy
Cancer treatment
Biocompatibility
status_str publishedVersion
title The Emerging Role of MXenes in Cancer Treatment
title_full The Emerging Role of MXenes in Cancer Treatment
title_fullStr The Emerging Role of MXenes in Cancer Treatment
title_full_unstemmed The Emerging Role of MXenes in Cancer Treatment
title_short The Emerging Role of MXenes in Cancer Treatment
title_sort The Emerging Role of MXenes in Cancer Treatment
topic MXenes
2D nanomaterials
Photothermal therapy
Cancer treatment
Biocompatibility
url https://hdl.handle.net/11073/33244