Human factors frameworks in analysis of contributory factors to medication error: A systematic review

BackgroundMedication safety remains a significant concern within healthcare systems globally. Identifying the factors that contribute to medication errors is essential for enhancing patient safety. Human factor (HF) frameworks address this by providing a comprehensive and systematic methodology for...

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Main Author: Duha, Rashdan (author)
Other Authors: Farha, Rana Abu (author), Yasin, Haya (author), Hadi, Muhammad Abdul (author)
Format: article
Published: 2025
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Online Access:http://dx.doi.org/10.1016/j.sapharm.2025.04.005
https://www.sciencedirect.com/science/article/pii/S1551741125002165
http://hdl.handle.net/10576/65525
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author Duha, Rashdan
author2 Farha, Rana Abu
Yasin, Haya
Hadi, Muhammad Abdul
author2_role author
author
author
author_facet Duha, Rashdan
Farha, Rana Abu
Yasin, Haya
Hadi, Muhammad Abdul
author_role author
dc.creator.none.fl_str_mv Duha, Rashdan
Farha, Rana Abu
Yasin, Haya
Hadi, Muhammad Abdul
dc.date.none.fl_str_mv 2025-06-15T07:44:13Z
2025-04-19
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://dx.doi.org/10.1016/j.sapharm.2025.04.005
Rashdan, D., Farha, R. A., Yasin, H., & Hadi, M. A. (2025). Human Factors Frameworks in Analysis of Contributory Factors to Medication Error: A Systematic Review. Research in Social and Administrative Pharmacy.
1551-7411
https://www.sciencedirect.com/science/article/pii/S1551741125002165
http://hdl.handle.net/10576/65525
1934-8150
dc.language.none.fl_str_mv en
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv reliability metrics
human factors
dc.title.none.fl_str_mv Human factors frameworks in analysis of contributory factors to medication error: A systematic review
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description BackgroundMedication safety remains a significant concern within healthcare systems globally. Identifying the factors that contribute to medication errors is essential for enhancing patient safety. Human factor (HF) frameworks address this by providing a comprehensive and systematic methodology for analysing these factors. AimThis systematic review aims to identify the various HF frameworks used for medication error analysis in healthcare, synthesise reported contributory factors, and assess the reliability metrics of these frameworks. MethodA comprehensive search of electronic databases (Medline, Embase, PsycINFO, Web of Science, SCOPUS, and ProQuest) was performed. Studies analysed contributory factors to medication errors using a validated HF Framework were included. HF frameworks results were synthesized narratively, and the contributory factors were synthesized using the Human factors analysis and classification system (HFACS) framework. ResultsThis review included 43 studies that took place in 16 different countries between 2002 and 2024. eleven HF frameworks were used to analyse medication errors, with Reason's model as the most frequently utilized. Communication factors, adverse mental status, physical and mental limitations, skill-based errors, and organizational influences were frequently reported factors contributing to medication errors. A limited number of studies reported any reliability metrics of the utilized framework. ConclusionHF frameworks are a valuable tool for analysing contributory factors to medication errors. There is a need to prioritise clear communication processes, optimize resource management, invest in continuous staff development, and consider external influences in medication safety strategies.Registry and registry number for systematic reviews or meta-analyses. the protocol applied in this study was registered in PROSPERO (registration number: CRD42024497681).
eu_rights_str_mv openAccess
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identifier_str_mv Rashdan, D., Farha, R. A., Yasin, H., & Hadi, M. A. (2025). Human Factors Frameworks in Analysis of Contributory Factors to Medication Error: A Systematic Review. Research in Social and Administrative Pharmacy.
1551-7411
1934-8150
language_invalid_str_mv en
network_acronym_str qu
network_name_str Qatar University repository
oai_identifier_str oai:qspace.qu.edu.qa:10576/65525
publishDate 2025
publisher.none.fl_str_mv Elsevier
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rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
spelling Human factors frameworks in analysis of contributory factors to medication error: A systematic reviewDuha, RashdanFarha, Rana AbuYasin, HayaHadi, Muhammad Abdulreliability metricshuman factorsBackgroundMedication safety remains a significant concern within healthcare systems globally. Identifying the factors that contribute to medication errors is essential for enhancing patient safety. Human factor (HF) frameworks address this by providing a comprehensive and systematic methodology for analysing these factors. AimThis systematic review aims to identify the various HF frameworks used for medication error analysis in healthcare, synthesise reported contributory factors, and assess the reliability metrics of these frameworks. MethodA comprehensive search of electronic databases (Medline, Embase, PsycINFO, Web of Science, SCOPUS, and ProQuest) was performed. Studies analysed contributory factors to medication errors using a validated HF Framework were included. HF frameworks results were synthesized narratively, and the contributory factors were synthesized using the Human factors analysis and classification system (HFACS) framework. ResultsThis review included 43 studies that took place in 16 different countries between 2002 and 2024. eleven HF frameworks were used to analyse medication errors, with Reason's model as the most frequently utilized. Communication factors, adverse mental status, physical and mental limitations, skill-based errors, and organizational influences were frequently reported factors contributing to medication errors. A limited number of studies reported any reliability metrics of the utilized framework. ConclusionHF frameworks are a valuable tool for analysing contributory factors to medication errors. There is a need to prioritise clear communication processes, optimize resource management, invest in continuous staff development, and consider external influences in medication safety strategies.Registry and registry number for systematic reviews or meta-analyses. the protocol applied in this study was registered in PROSPERO (registration number: CRD42024497681).Elsevier2025-06-15T07:44:13Z2025-04-19Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.sapharm.2025.04.005Rashdan, D., Farha, R. A., Yasin, H., & Hadi, M. A. (2025). Human Factors Frameworks in Analysis of Contributory Factors to Medication Error: A Systematic Review. Research in Social and Administrative Pharmacy.1551-7411https://www.sciencedirect.com/science/article/pii/S1551741125002165http://hdl.handle.net/10576/655251934-8150enhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/655252025-06-15T19:07:26Z
spellingShingle Human factors frameworks in analysis of contributory factors to medication error: A systematic review
Duha, Rashdan
reliability metrics
human factors
status_str publishedVersion
title Human factors frameworks in analysis of contributory factors to medication error: A systematic review
title_full Human factors frameworks in analysis of contributory factors to medication error: A systematic review
title_fullStr Human factors frameworks in analysis of contributory factors to medication error: A systematic review
title_full_unstemmed Human factors frameworks in analysis of contributory factors to medication error: A systematic review
title_short Human factors frameworks in analysis of contributory factors to medication error: A systematic review
title_sort Human factors frameworks in analysis of contributory factors to medication error: A systematic review
topic reliability metrics
human factors
url http://dx.doi.org/10.1016/j.sapharm.2025.04.005
https://www.sciencedirect.com/science/article/pii/S1551741125002165
http://hdl.handle.net/10576/65525