Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines

Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines

The aim of this study is to investigate using nanoemulsion formulations as drug-delivery vehicles of paclitaxel (PX), a poor water-soluble anticancer drug. Two commercially available nanoemulsion fat formulations (Clinoleic 20% and Intralipid 20%) were loaded with PX and characterised based on their...

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Bibliographic Details
Main Author: Najlah, Mohammad (author)
Other Authors: Kadam, Alisha (author), Wan, Ka-Wai (author), Ahmed, Waqar (author), Taylor, Kevin M.G. (author), Elhissi, Abdelbary M.A (author)
Format: article
Published: 2016
Subjects:
Droplet size
Nanoemulsion
Paclitaxel
Stability
Anticancer
MTT assay
Online Access:http://dx.doi.org/10.1016/j.ijpharm.2016.04.027
http://www.sciencedirect.com/science/article/pii/S0378517316303118
http://hdl.handle.net/10576/4914
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http://dx.doi.org/10.1016/j.ijpharm.2016.04.027
http://www.sciencedirect.com/science/article/pii/S0378517316303118
http://hdl.handle.net/10576/4914

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