Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour
Early implant failure and bone resorption may occur in load-bearing conditions as a result of stress shielding brought on by a mismatch in the bone-Ti-implant modulus. A review with a novel multidisciplinary perspective is proposed in this work, which considers recent developments of β-Titanium allo...
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| مؤلفون آخرون: | , , , , , , , |
| التنسيق: | article |
| منشور في: |
2024
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://dx.doi.org/10.1016/j.jmrt.2024.09.248 https://www.sciencedirect.com/science/article/pii/S2238785424022531 http://hdl.handle.net/10576/64367 |
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| _version_ | 1857415085883916288 |
|---|---|
| author | Elhadad, Amir A. |
| author2 | Romero-Resendiz, L. Rossi, M.C. Rodríguez-Albelo, L.M. Lascano, Sheila Afonso, Conrado R.M. Alcudia, A. Amigó, V. Torres, Y. |
| author2_role | author author author author author author author author |
| author_facet | Elhadad, Amir A. Romero-Resendiz, L. Rossi, M.C. Rodríguez-Albelo, L.M. Lascano, Sheila Afonso, Conrado R.M. Alcudia, A. Amigó, V. Torres, Y. |
| author_role | author |
| dc.creator.none.fl_str_mv | Elhadad, Amir A. Romero-Resendiz, L. Rossi, M.C. Rodríguez-Albelo, L.M. Lascano, Sheila Afonso, Conrado R.M. Alcudia, A. Amigó, V. Torres, Y. |
| dc.date.none.fl_str_mv | 2024-12-31 2025-04-22T05:27:03Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://dx.doi.org/10.1016/j.jmrt.2024.09.248 22387854 https://www.sciencedirect.com/science/article/pii/S2238785424022531 http://hdl.handle.net/10576/64367 3550-3618 33 2214-0697 |
| dc.language.none.fl_str_mv | en |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Beta-titanium alloys Novel manufacturing routes Surface modification treatments Bio-functional and tribomechanical behaviour Cellular and bacterial response |
| dc.title.none.fl_str_mv | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Early implant failure and bone resorption may occur in load-bearing conditions as a result of stress shielding brought on by a mismatch in the bone-Ti-implant modulus. A review with a novel multidisciplinary perspective is proposed in this work, which considers recent developments of β-Titanium alloys and new trends in novel microstructures, processing techniques, properties of dense and porous substrates, as well as the relationship between all these aspects and performance in service, in terms of improved its biomechanical and bio-functional balance. In addition to highlighting several modern and historical uses for Ti alloys, this review covers many cutting-edge novel β-Ti alloys and uses that promise to exceed historical standards. Also, it deepens through several important properties of these alloys, including toxicity of alloying elements, phase stability, thermo-mechanical processing, heat treatment, surface, and stress-induced modifications. The stiffness, hardness, fatigue and wear resistance, corrosion behaviour, biocompatibility, and manufacturing and surface modification effects on these parameters are also emphasized. In-vitro and in-vivo assays have been added to highlight important aspects of bioactivity and antibacterial behaviour, and future significant research areas are suggested along with new techniques to ensure the successful clinical application of β-Ti alloys. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | qu_52ec3d4fa91b302f8ca5dcd1d0af3947 |
| identifier_str_mv | 22387854 3550-3618 33 2214-0697 |
| language_invalid_str_mv | en |
| network_acronym_str | qu |
| network_name_str | Qatar University repository |
| oai_identifier_str | oai:qspace.qu.edu.qa:10576/64367 |
| publishDate | 2024 |
| publisher.none.fl_str_mv | Elsevier |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc/4.0/ |
| spelling | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviourElhadad, Amir A.Romero-Resendiz, L.Rossi, M.C.Rodríguez-Albelo, L.M.Lascano, SheilaAfonso, Conrado R.M.Alcudia, A.Amigó, V.Torres, Y.Beta-titanium alloysNovel manufacturing routesSurface modification treatmentsBio-functional and tribomechanical behaviourCellular and bacterial responseEarly implant failure and bone resorption may occur in load-bearing conditions as a result of stress shielding brought on by a mismatch in the bone-Ti-implant modulus. A review with a novel multidisciplinary perspective is proposed in this work, which considers recent developments of β-Titanium alloys and new trends in novel microstructures, processing techniques, properties of dense and porous substrates, as well as the relationship between all these aspects and performance in service, in terms of improved its biomechanical and bio-functional balance. In addition to highlighting several modern and historical uses for Ti alloys, this review covers many cutting-edge novel β-Ti alloys and uses that promise to exceed historical standards. Also, it deepens through several important properties of these alloys, including toxicity of alloying elements, phase stability, thermo-mechanical processing, heat treatment, surface, and stress-induced modifications. The stiffness, hardness, fatigue and wear resistance, corrosion behaviour, biocompatibility, and manufacturing and surface modification effects on these parameters are also emphasized. In-vitro and in-vivo assays have been added to highlight important aspects of bioactivity and antibacterial behaviour, and future significant research areas are suggested along with new techniques to ensure the successful clinical application of β-Ti alloys.This publication has been part of the following projects: - R+D+i projects PDC2022-133369-I00 and PID2022-137911OB-I00, financed by MCIN/AEI/10.13039/501100011033/ - CNPq Universal Project #422015/2018-0 (C.R.M.A.); - FAPESP (São Paulo Research Foundation) for financial support through “Projeto Temático” # 2018/18293-8, post doc Grant # 2021/03865-9 (M.C.R.)Elsevier2025-04-22T05:27:03Z2024-12-31Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.jmrt.2024.09.24822387854https://www.sciencedirect.com/science/article/pii/S2238785424022531http://hdl.handle.net/10576/643673550-3618332214-0697enhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/643672025-04-22T19:05:42Z |
| spellingShingle | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour Elhadad, Amir A. Beta-titanium alloys Novel manufacturing routes Surface modification treatments Bio-functional and tribomechanical behaviour Cellular and bacterial response |
| status_str | publishedVersion |
| title | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| title_full | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| title_fullStr | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| title_full_unstemmed | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| title_short | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| title_sort | Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour |
| topic | Beta-titanium alloys Novel manufacturing routes Surface modification treatments Bio-functional and tribomechanical behaviour Cellular and bacterial response |
| url | http://dx.doi.org/10.1016/j.jmrt.2024.09.248 https://www.sciencedirect.com/science/article/pii/S2238785424022531 http://hdl.handle.net/10576/64367 |