Race/ethnicity and challenges for optimal insulin therapy
AimsWe aimed to review insulin dosing recommendations, insulin regulation and its determinants, glycaemic response to carbohydrates, and the efficacy and safety of insulin therapy in different races/ethnicities. MethodsWe searched for articles in PubMed and Google Scholar databases up to 31 March 20...
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| مؤلفون آخرون: | , , , , , , , , , , , , , , , |
| التنسيق: | article |
| منشور في: |
2021
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://dx.doi.org/10.1016/j.diabres.2021.108823 https://www.sciencedirect.com/science/article/pii/S0168822721001820 http://hdl.handle.net/10576/20601 |
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| _version_ | 1857415084453658624 |
|---|---|
| author | Nayla Cristina, do Vale Moreira |
| author2 | Ceriello, Antonio Basit, Abdul Balde, Naby Mohan, V. Gupta, Ritesh Misra, Anoop Bhowmik, Bishwajit Lee, Moon K. Zuo, Hui Shi, Zumin Wang, Youfa Montenegro, Renan M. Fernandes, Virgínia Oliveira Colagiuri, Stephen Boulton, Andrew J.M. Hussain, Akhtar |
| author2_role | author author author author author author author author author author author author author author author author |
| author_facet | Nayla Cristina, do Vale Moreira Ceriello, Antonio Basit, Abdul Balde, Naby Mohan, V. Gupta, Ritesh Misra, Anoop Bhowmik, Bishwajit Lee, Moon K. Zuo, Hui Shi, Zumin Wang, Youfa Montenegro, Renan M. Fernandes, Virgínia Oliveira Colagiuri, Stephen Boulton, Andrew J.M. Hussain, Akhtar |
| author_role | author |
| dc.creator.none.fl_str_mv | Nayla Cristina, do Vale Moreira Ceriello, Antonio Basit, Abdul Balde, Naby Mohan, V. Gupta, Ritesh Misra, Anoop Bhowmik, Bishwajit Lee, Moon K. Zuo, Hui Shi, Zumin Wang, Youfa Montenegro, Renan M. Fernandes, Virgínia Oliveira Colagiuri, Stephen Boulton, Andrew J.M. Hussain, Akhtar |
| dc.date.none.fl_str_mv | 2021-06-13T06:19:27Z 2021-05-31 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://dx.doi.org/10.1016/j.diabres.2021.108823 do Vale Moreira NC, Ceriello A, Basit A, Balde N, Mohan V, Gupta R, Misra A, Bhowmik B, Lee MK, Zuo H, Shi Z, Wang Y, Montenegro RM, Fernandes VO, Colagiuri S, Boulton AJM, Hussain A. Race/ethnicity and challenges for optimal insulin therapy. Diabetes Res Clin Pract. 2021 Apr 20;175:108823. doi: 10.1016/j.diabres.2021.108823. 01688227 https://www.sciencedirect.com/science/article/pii/S0168822721001820 http://hdl.handle.net/10576/20601 175 |
| dc.language.none.fl_str_mv | en |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Race Ethnicity Diabetes Insulin sensitivity Insulin resistance Insulin therapy |
| dc.title.none.fl_str_mv | Race/ethnicity and challenges for optimal insulin therapy |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | AimsWe aimed to review insulin dosing recommendations, insulin regulation and its determinants, glycaemic response to carbohydrates, and the efficacy and safety of insulin therapy in different races/ethnicities. MethodsWe searched for articles in PubMed and Google Scholar databases up to 31 March 2021, with the following keywords: “ethnicity”, “diabetes”, “insulin”, “history of insulin”, “insulin therapy”, “food/rice”, “carbohydrate intake”, “insulin resistance”, “BMI”, “insulin dosing”, “insulin sensitivity”, “insulin response”, “glycaemic index”, “glycaemic response”, “efficacy and safety”, with interposition of the Boolean operator “AND”.In addition, we reviewed the reference lists of the articles found. ResultsThe differential effect of race/ethnicity has not yet been considered in current insulin therapy guidelines. Nevertheless, body size and composition, body mass index, fat distribution, diet, storage, and energy expenditure vary significantly across populations. Further, insulin sensitivity, insulin response, and glycaemicresponse to carbohydrates differ by ethnicity. These disparities may lead to different insulin requirements, adversely impacting the efficacy and safety of insulin therapy among ethnic groups. ConclusionsRace/ethnicity affects glucose metabolism and insulin regulation.Until now, international guidelines addressing racial/ethnic-specific clinical recommendations are limited. Comprehensive updated insulin therapy guidelines by ethnicity are urgently needed. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | qu_5a85b30ff914c41eb45d2ef42517f7a0 |
| identifier_str_mv | do Vale Moreira NC, Ceriello A, Basit A, Balde N, Mohan V, Gupta R, Misra A, Bhowmik B, Lee MK, Zuo H, Shi Z, Wang Y, Montenegro RM, Fernandes VO, Colagiuri S, Boulton AJM, Hussain A. Race/ethnicity and challenges for optimal insulin therapy. Diabetes Res Clin Pract. 2021 Apr 20;175:108823. doi: 10.1016/j.diabres.2021.108823. 01688227 175 |
| language_invalid_str_mv | en |
| network_acronym_str | qu |
| network_name_str | Qatar University repository |
| oai_identifier_str | oai:qspace.qu.edu.qa:10576/20601 |
| publishDate | 2021 |
| publisher.none.fl_str_mv | Elsevier |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| spelling | Race/ethnicity and challenges for optimal insulin therapyNayla Cristina, do Vale MoreiraCeriello, AntonioBasit, AbdulBalde, NabyMohan, V.Gupta, RiteshMisra, AnoopBhowmik, BishwajitLee, Moon K.Zuo, HuiShi, ZuminWang, YoufaMontenegro, Renan M.Fernandes, Virgínia OliveiraColagiuri, StephenBoulton, Andrew J.M.Hussain, AkhtarRaceEthnicityDiabetesInsulin sensitivityInsulin resistanceInsulin therapyAimsWe aimed to review insulin dosing recommendations, insulin regulation and its determinants, glycaemic response to carbohydrates, and the efficacy and safety of insulin therapy in different races/ethnicities. MethodsWe searched for articles in PubMed and Google Scholar databases up to 31 March 2021, with the following keywords: “ethnicity”, “diabetes”, “insulin”, “history of insulin”, “insulin therapy”, “food/rice”, “carbohydrate intake”, “insulin resistance”, “BMI”, “insulin dosing”, “insulin sensitivity”, “insulin response”, “glycaemic index”, “glycaemic response”, “efficacy and safety”, with interposition of the Boolean operator “AND”.In addition, we reviewed the reference lists of the articles found. ResultsThe differential effect of race/ethnicity has not yet been considered in current insulin therapy guidelines. Nevertheless, body size and composition, body mass index, fat distribution, diet, storage, and energy expenditure vary significantly across populations. Further, insulin sensitivity, insulin response, and glycaemicresponse to carbohydrates differ by ethnicity. These disparities may lead to different insulin requirements, adversely impacting the efficacy and safety of insulin therapy among ethnic groups. ConclusionsRace/ethnicity affects glucose metabolism and insulin regulation.Until now, international guidelines addressing racial/ethnic-specific clinical recommendations are limited. Comprehensive updated insulin therapy guidelines by ethnicity are urgently needed.Elsevier2021-06-13T06:19:27Z2021-05-31Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.diabres.2021.108823do Vale Moreira NC, Ceriello A, Basit A, Balde N, Mohan V, Gupta R, Misra A, Bhowmik B, Lee MK, Zuo H, Shi Z, Wang Y, Montenegro RM, Fernandes VO, Colagiuri S, Boulton AJM, Hussain A. Race/ethnicity and challenges for optimal insulin therapy. Diabetes Res Clin Pract. 2021 Apr 20;175:108823. doi: 10.1016/j.diabres.2021.108823.01688227https://www.sciencedirect.com/science/article/pii/S0168822721001820http://hdl.handle.net/10576/20601175enhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/206012024-07-23T11:23:42Z |
| spellingShingle | Race/ethnicity and challenges for optimal insulin therapy Nayla Cristina, do Vale Moreira Race Ethnicity Diabetes Insulin sensitivity Insulin resistance Insulin therapy |
| status_str | publishedVersion |
| title | Race/ethnicity and challenges for optimal insulin therapy |
| title_full | Race/ethnicity and challenges for optimal insulin therapy |
| title_fullStr | Race/ethnicity and challenges for optimal insulin therapy |
| title_full_unstemmed | Race/ethnicity and challenges for optimal insulin therapy |
| title_short | Race/ethnicity and challenges for optimal insulin therapy |
| title_sort | Race/ethnicity and challenges for optimal insulin therapy |
| topic | Race Ethnicity Diabetes Insulin sensitivity Insulin resistance Insulin therapy |
| url | http://dx.doi.org/10.1016/j.diabres.2021.108823 https://www.sciencedirect.com/science/article/pii/S0168822721001820 http://hdl.handle.net/10576/20601 |