Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy

Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy

IntroductionActivating the aryl hydrocarbon receptor upon exposure to environmental pollutants promotes development of breast cancer stem cell (CSCs). BCL-2 family proteins protect cancer cells from the apoptotic effects of chemotherapeutic drugs. However, the crosstalk between AhR and the BCL-2 fam...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Abdullah, Al-Dhfyan (author)
مؤلفون آخرون:	Alaiya, Ayodele (author), Al-Mohanna, Falah (author), Attwa, Mohamed W (author), AlAsmari, Abdullah F (author), Bakheet, Saleh A (author), Korashy, Hesham M. (author)
التنسيق:	article
منشور في:	2022
الموضوعات:	AhR/CYP1A1 Breast cancer stem cells In vivo mice BCL-2 Proteomics Venetoclax
الوصول للمادة أونلاين:	http://dx.doi.org/10.1016/j.jare.2022.10.006 https://www.sciencedirect.com/science/article/pii/S209012322200234X http://hdl.handle.net/10576/41421
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

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