Regenerative potential of platelet concentrates in chronic oral mucosal lesions

Chronic oral mucosal diseases (COMDs) represent a significant challenge for clinicians and patients. They are commonly associated with chronic pain and negative effects on healing and patient's quality of life. Regenerative medicine including the use of biological autologous blood-derived subst...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Abdel-Hameed, Hijazi (author)
مؤلفون آخرون: Al-Hamed, Faez Saleh (author), Tamimi, Faleh (author), Al-Maweri, Sadeq A. (author), Hamdan, Nader (author), Psutka, David J. (author), Ta, Peter (author), Klieb, Hagen (author)
التنسيق: article
منشور في: 2024
الموضوعات:
الوصول للمادة أونلاين:http://dx.doi.org/10.1016/j.jobcr.2024.02.007
https://www.sciencedirect.com/science/article/pii/S2212426824000307
http://hdl.handle.net/10576/53876
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author Abdel-Hameed, Hijazi
author2 Al-Hamed, Faez Saleh
Tamimi, Faleh
Al-Maweri, Sadeq A.
Hamdan, Nader
Psutka, David J.
Ta, Peter
Klieb, Hagen
author2_role author
author
author
author
author
author
author
author_facet Abdel-Hameed, Hijazi
Al-Hamed, Faez Saleh
Tamimi, Faleh
Al-Maweri, Sadeq A.
Hamdan, Nader
Psutka, David J.
Ta, Peter
Klieb, Hagen
author_role author
dc.creator.none.fl_str_mv Abdel-Hameed, Hijazi
Al-Hamed, Faez Saleh
Tamimi, Faleh
Al-Maweri, Sadeq A.
Hamdan, Nader
Psutka, David J.
Ta, Peter
Klieb, Hagen
dc.date.none.fl_str_mv 2024-04-03T08:58:09Z
2024-04-30
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://dx.doi.org/10.1016/j.jobcr.2024.02.007
22124268
https://www.sciencedirect.com/science/article/pii/S2212426824000307
http://hdl.handle.net/10576/53876
216-221
2
14
2212-4276
dc.language.none.fl_str_mv en
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Platelet-rich plasma
Platelet-rich fibrin
Platelet concentrates
Oral lesions
Oral ulcers
dc.title.none.fl_str_mv Regenerative potential of platelet concentrates in chronic oral mucosal lesions
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Chronic oral mucosal diseases (COMDs) represent a significant challenge for clinicians and patients. They are commonly associated with chronic pain and negative effects on healing and patient's quality of life. Regenerative medicine including the use of biological autologous blood-derived substances (e.g., platelet concentrates [PCs]), has been reported to improve healing and reduce pain in orthopedic and maxillofacial surgeries as well as chronic oral mucosal diseases. In this review, we aim to describe the different types of PCs and their applications in the management of COMDs such as lichen planus, mucositis, pemphigus vulgaris, mucous membrane pemphigoid, and plasma cell mucositis, in terms of healing potential, pain control, and quality of life. Overall, PC applications seem to enhance healing and reduce pain in patients with COMDs. However, due to the small sample size and the lack of standardized clinical trials, further research is required to support these findings.
eu_rights_str_mv openAccess
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network_acronym_str qu
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publishDate 2024
publisher.none.fl_str_mv Elsevier
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spelling Regenerative potential of platelet concentrates in chronic oral mucosal lesionsAbdel-Hameed, HijaziAl-Hamed, Faez SalehTamimi, FalehAl-Maweri, Sadeq A.Hamdan, NaderPsutka, David J.Ta, PeterKlieb, HagenPlatelet-rich plasmaPlatelet-rich fibrinPlatelet concentratesOral lesionsOral ulcersChronic oral mucosal diseases (COMDs) represent a significant challenge for clinicians and patients. They are commonly associated with chronic pain and negative effects on healing and patient's quality of life. Regenerative medicine including the use of biological autologous blood-derived substances (e.g., platelet concentrates [PCs]), has been reported to improve healing and reduce pain in orthopedic and maxillofacial surgeries as well as chronic oral mucosal diseases. In this review, we aim to describe the different types of PCs and their applications in the management of COMDs such as lichen planus, mucositis, pemphigus vulgaris, mucous membrane pemphigoid, and plasma cell mucositis, in terms of healing potential, pain control, and quality of life. Overall, PC applications seem to enhance healing and reduce pain in patients with COMDs. However, due to the small sample size and the lack of standardized clinical trials, further research is required to support these findings.Elsevier2024-04-03T08:58:09Z2024-04-30Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.jobcr.2024.02.00722124268https://www.sciencedirect.com/science/article/pii/S2212426824000307http://hdl.handle.net/10576/53876216-2212142212-4276enhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/538762024-07-23T15:53:20Z
spellingShingle Regenerative potential of platelet concentrates in chronic oral mucosal lesions
Abdel-Hameed, Hijazi
Platelet-rich plasma
Platelet-rich fibrin
Platelet concentrates
Oral lesions
Oral ulcers
status_str publishedVersion
title Regenerative potential of platelet concentrates in chronic oral mucosal lesions
title_full Regenerative potential of platelet concentrates in chronic oral mucosal lesions
title_fullStr Regenerative potential of platelet concentrates in chronic oral mucosal lesions
title_full_unstemmed Regenerative potential of platelet concentrates in chronic oral mucosal lesions
title_short Regenerative potential of platelet concentrates in chronic oral mucosal lesions
title_sort Regenerative potential of platelet concentrates in chronic oral mucosal lesions
topic Platelet-rich plasma
Platelet-rich fibrin
Platelet concentrates
Oral lesions
Oral ulcers
url http://dx.doi.org/10.1016/j.jobcr.2024.02.007
https://www.sciencedirect.com/science/article/pii/S2212426824000307
http://hdl.handle.net/10576/53876