Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer

Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer

BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. It is driven by HER2 oncoprotein activation/crosstalk with other receptors like EGFR/(HER1), HER3, and HER4, in addition to IGF-1R, making these receptors ideal therapeutic targets as they are expressed/overexpres...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Kheraldine, Hadeel (author)
مؤلفون آخرون:	Hassan, Arij Fouzat (author), Saeed, Sumayyah (author), Merhi, Maysaloun (author), Mateo, Jericha Miles (author), Ulamec, Monika (author), Peric-Balja, Melita (author), Vranic, Semir (author), Al-Thawadi, Hamda (author), Moustafa, Ala-Eddin Al (author)
التنسيق:	article
منشور في:	2025
الموضوعات:	HER2-positive breast cancer Neratinib Metformin EGFR HER3 IGF-1R Angiogenesis
الوصول للمادة أونلاين:	http://dx.doi.org/10.1016/j.biopha.2025.118034 https://www.sciencedirect.com/science/article/pii/S0753332225002288 http://hdl.handle.net/10576/65155
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

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