Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies

Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. Metformin shows anti-tumor activities in several cancer types. How...

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Bibliographic Details
Main Author: Fawaz E., Alanazi (author)
Other Authors: As Sobeai, Homood M. (author), Alhazzani, Khalid (author), Al-Dhfyan, Abdullah (author), Alshammari, Musaad A (author), Alotaibi, Moureq (author), Al-hosaini, Khaled (author), Korashy, Hesham M. (author), Alhoshani, Ali (author)
Format: article
Published: 2021
Subjects:
VISTA
AHR
CYP1A1
IDO1
Metformin
CHL-1
B16
Melanoma
Online Access:http://dx.doi.org/10.1016/j.jsps.2021.12.014
https://www.sciencedirect.com/science/article/pii/S1319016421002632
http://hdl.handle.net/10576/41172
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