Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions suggesting that their activities might be interrelated. The inhibition of NHE1 has b...
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| Format: | article |
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2020
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| Online Access: | http://dx.doi.org/10.1016/j.ejphar.2020.173420 https://www.sciencedirect.com/science/article/pii/S0014299920305124 http://hdl.handle.net/10576/44612 |
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