Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish

Chemicals are at the top of public health concerns and metals have received much attention in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic heavy metals and are widely distributed in the environment. They are considered important factors involved in several o...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Azza, Naija (author)
مؤلفون آخرون: Yalcin, Huseyin Cagatay (author)
التنسيق: article
منشور في: 2023
الموضوعات:
الوصول للمادة أونلاين:http://dx.doi.org/10.1016/j.toxrep.2023.04.009
https://www.sciencedirect.com/science/article/pii/S2214750023000458
http://hdl.handle.net/10576/42152
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author Azza, Naija
author2 Yalcin, Huseyin Cagatay
author2_role author
author_facet Azza, Naija
Yalcin, Huseyin Cagatay
author_role author
dc.creator.none.fl_str_mv Azza, Naija
Yalcin, Huseyin Cagatay
dc.date.none.fl_str_mv 2023-04-30T08:09:01Z
2023-12-31
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://dx.doi.org/10.1016/j.toxrep.2023.04.009
Naija, Azza, and Huseyin Cagatay Yalcin. "EVALUATION OF CADMIUM AND MERCURY ON CARDIOVASCULAR AND NEUROLOGICAL SYSTEMS: EFFECTS ON HUMANS AND FISH." Toxicology Reports (2023).
22147500
https://www.sciencedirect.com/science/article/pii/S2214750023000458
http://hdl.handle.net/10576/42152
498-508
10
dc.language.none.fl_str_mv en
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cadmium
Mercury
Fish
Humans
Heart
Brain
dc.title.none.fl_str_mv Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Chemicals are at the top of public health concerns and metals have received much attention in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic heavy metals and are widely distributed in the environment. They are considered important factors involved in several organ disturbances. Heart and brain tissues are not among the first exposure sites to Cd and Hg but they are directly affected and may manifest intoxication reactions leading to death. Many cases of human intoxication with Cd and Hg showed that these metals have potential cardiotoxic and neurotoxic effects. Human exposure to heavy metals is through fish consumption which is considered as an excellent source of human nutrients. In the current review, we will summarize the most known cases of human intoxication with Cd and Hg, highlight their toxic effects on fish, and investigate the common signal pathways of both Cd and Hg to affect heart and brain tissues. Also, we will present the most common biomarkers used in the assessment of cardiotoxicity and neurotoxicity using Zebrafish model.
eu_rights_str_mv openAccess
format article
id qu_d357b9d221a11130b70a0749d6084bba
identifier_str_mv Naija, Azza, and Huseyin Cagatay Yalcin. "EVALUATION OF CADMIUM AND MERCURY ON CARDIOVASCULAR AND NEUROLOGICAL SYSTEMS: EFFECTS ON HUMANS AND FISH." Toxicology Reports (2023).
22147500
498-508
10
language_invalid_str_mv en
network_acronym_str qu
network_name_str Qatar University repository
oai_identifier_str oai:qspace.qu.edu.qa:10576/42152
publishDate 2023
publisher.none.fl_str_mv Elsevier
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
spelling Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fishAzza, NaijaYalcin, Huseyin CagatayCadmiumMercuryFishHumansHeartBrainChemicals are at the top of public health concerns and metals have received much attention in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic heavy metals and are widely distributed in the environment. They are considered important factors involved in several organ disturbances. Heart and brain tissues are not among the first exposure sites to Cd and Hg but they are directly affected and may manifest intoxication reactions leading to death. Many cases of human intoxication with Cd and Hg showed that these metals have potential cardiotoxic and neurotoxic effects. Human exposure to heavy metals is through fish consumption which is considered as an excellent source of human nutrients. In the current review, we will summarize the most known cases of human intoxication with Cd and Hg, highlight their toxic effects on fish, and investigate the common signal pathways of both Cd and Hg to affect heart and brain tissues. Also, we will present the most common biomarkers used in the assessment of cardiotoxicity and neurotoxicity using Zebrafish model.The open-access finding of the present work is provided by the Qatar National Library (QATAR).Elsevier2023-04-30T08:09:01Z2023-12-31Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.toxrep.2023.04.009Naija, Azza, and Huseyin Cagatay Yalcin. "EVALUATION OF CADMIUM AND MERCURY ON CARDIOVASCULAR AND NEUROLOGICAL SYSTEMS: EFFECTS ON HUMANS AND FISH." Toxicology Reports (2023).22147500https://www.sciencedirect.com/science/article/pii/S2214750023000458http://hdl.handle.net/10576/42152498-50810enhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/421522024-07-23T13:53:02Z
spellingShingle Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
Azza, Naija
Cadmium
Mercury
Fish
Humans
Heart
Brain
status_str publishedVersion
title Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
title_full Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
title_fullStr Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
title_full_unstemmed Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
title_short Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
title_sort Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
topic Cadmium
Mercury
Fish
Humans
Heart
Brain
url http://dx.doi.org/10.1016/j.toxrep.2023.04.009
https://www.sciencedirect.com/science/article/pii/S2214750023000458
http://hdl.handle.net/10576/42152