Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials
AimsWeight reduction is fundamental for the management and remission of diabetes. We aimed to assess ethnic differences in the effects of lifestyle weight-loss interventions on HbA1c levels in overweight or obese adults with type 2 diabetes mellitus (T2DM). MethodsWe systematically searched PubMed/M...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , , , , , , |
| التنسيق: | article |
| منشور في: |
2023
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | http://dx.doi.org/10.1016/j.diabres.2023.110662 https://www.sciencedirect.com/science/article/pii/S0168822723004229 http://hdl.handle.net/10576/42660 |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1857415084989480960 |
|---|---|
| author | Jie, Yang |
| author2 | Xia, Yujia Sun, Yanan Guo, Yufei Shi, Zumin Cristina do Vale Moreira, Nayla Zuo, Hui Hussain, Akhtar |
| author2_role | author author author author author author author |
| author_facet | Jie, Yang Xia, Yujia Sun, Yanan Guo, Yufei Shi, Zumin Cristina do Vale Moreira, Nayla Zuo, Hui Hussain, Akhtar |
| author_role | author |
| dc.creator.none.fl_str_mv | Jie, Yang Xia, Yujia Sun, Yanan Guo, Yufei Shi, Zumin Cristina do Vale Moreira, Nayla Zuo, Hui Hussain, Akhtar |
| dc.date.none.fl_str_mv | 2023-05-14T05:23:17Z 2023-05-31 |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://dx.doi.org/10.1016/j.diabres.2023.110662 Yang, J., Xia, Y., Sun, Y., Guo, Y., Shi, Z., do Vale Moreira, N. C., ... & Hussain, A. (2023). Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials. Diabetes Research and Clinical Practice, 110662. 01688227 https://www.sciencedirect.com/science/article/pii/S0168822723004229 http://hdl.handle.net/10576/42660 199 |
| dc.language.none.fl_str_mv | en |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Diabetes Lifestyle intervention HbA1c Ethnicity Weight loss Randomized controlled trial |
| dc.title.none.fl_str_mv | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | AimsWeight reduction is fundamental for the management and remission of diabetes. We aimed to assess ethnic differences in the effects of lifestyle weight-loss interventions on HbA1c levels in overweight or obese adults with type 2 diabetes mellitus (T2DM). MethodsWe systematically searched PubMed/MEDLINE and Web of Science online databases up to 31 Dec 2022. Randomized controlled trials using lifestyle weight-loss interventions in overweight or obese adults with T2DM were selected. We performed subgroup analyses to explore the heterogeneity across different ethnicities (Asians, White/Caucasians, Black/Africans and Hispanics). A random effects model was applied to calculate weighted mean difference (WMD) with 95% confidence interval (CI). ResultsThirty studies including 7580 subjects from different ethnicities were identified according to the predefined inclusion and exclusion criteria. HbA1c levels were significantly reduced by lifestyle weight-loss intervention. Notably, a significantly beneficial effect on HbA1c was observed in White/Caucasians (WMD = -0.59, 95% CI: −0.90, −0.28, P < 0.001) and Asians (WMD = -0.48, 95% CI: −0.63, −0.33, P < 0.001), but not in the Black/African or Hispanic group (both P > 0.05). The findings remained essentially unchanged in the sensitivity analysis. ConclusionsLifestyle weight-loss interventions had distinct beneficial effects on HbA1c levels in different ethnic groups with T2DM, especially in Caucasians and Asians. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | qu_d4cb0f759c7020d39aec3191de7f8096 |
| identifier_str_mv | Yang, J., Xia, Y., Sun, Y., Guo, Y., Shi, Z., do Vale Moreira, N. C., ... & Hussain, A. (2023). Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials. Diabetes Research and Clinical Practice, 110662. 01688227 199 |
| language_invalid_str_mv | en |
| network_acronym_str | qu |
| network_name_str | Qatar University repository |
| oai_identifier_str | oai:qspace.qu.edu.qa:10576/42660 |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Elsevier |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| spelling | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trialsJie, YangXia, YujiaSun, YananGuo, YufeiShi, ZuminCristina do Vale Moreira, NaylaZuo, HuiHussain, AkhtarDiabetesLifestyle interventionHbA1cEthnicityWeight lossRandomized controlled trialAimsWeight reduction is fundamental for the management and remission of diabetes. We aimed to assess ethnic differences in the effects of lifestyle weight-loss interventions on HbA1c levels in overweight or obese adults with type 2 diabetes mellitus (T2DM). MethodsWe systematically searched PubMed/MEDLINE and Web of Science online databases up to 31 Dec 2022. Randomized controlled trials using lifestyle weight-loss interventions in overweight or obese adults with T2DM were selected. We performed subgroup analyses to explore the heterogeneity across different ethnicities (Asians, White/Caucasians, Black/Africans and Hispanics). A random effects model was applied to calculate weighted mean difference (WMD) with 95% confidence interval (CI). ResultsThirty studies including 7580 subjects from different ethnicities were identified according to the predefined inclusion and exclusion criteria. HbA1c levels were significantly reduced by lifestyle weight-loss intervention. Notably, a significantly beneficial effect on HbA1c was observed in White/Caucasians (WMD = -0.59, 95% CI: −0.90, −0.28, P < 0.001) and Asians (WMD = -0.48, 95% CI: −0.63, −0.33, P < 0.001), but not in the Black/African or Hispanic group (both P > 0.05). The findings remained essentially unchanged in the sensitivity analysis. ConclusionsLifestyle weight-loss interventions had distinct beneficial effects on HbA1c levels in different ethnic groups with T2DM, especially in Caucasians and Asians.Elsevier2023-05-14T05:23:17Z2023-05-31Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://dx.doi.org/10.1016/j.diabres.2023.110662Yang, J., Xia, Y., Sun, Y., Guo, Y., Shi, Z., do Vale Moreira, N. C., ... & Hussain, A. (2023). Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials. Diabetes Research and Clinical Practice, 110662.01688227https://www.sciencedirect.com/science/article/pii/S0168822723004229http://hdl.handle.net/10576/42660199enhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/426602024-07-23T13:53:11Z |
| spellingShingle | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials Jie, Yang Diabetes Lifestyle intervention HbA1c Ethnicity Weight loss Randomized controlled trial |
| status_str | publishedVersion |
| title | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| title_full | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| title_short | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| title_sort | Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials |
| topic | Diabetes Lifestyle intervention HbA1c Ethnicity Weight loss Randomized controlled trial |
| url | http://dx.doi.org/10.1016/j.diabres.2023.110662 https://www.sciencedirect.com/science/article/pii/S0168822723004229 http://hdl.handle.net/10576/42660 |