Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). We investigated...
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| Other Authors: | , , , , , |
| Format: | article |
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2023
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| Online Access: | http://dx.doi.org/10.1016/j.redox.2022.102574 https://www.sciencedirect.com/science/article/pii/S2213231722003469 http://hdl.handle.net/10576/44666 |
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