Molecular screening of phytocompounds targeting the interface between influenza A NS1 and TRIM25 to enhance host immune responses

Molecular screening of phytocompounds targeting the interface between influenza A NS1 and TRIM25 to enhance host immune responses

BackgroundInfluenza A virus causes severe respiratory illnesses, especially in developing nations where most child deaths under 5 occur due to lower respiratory tract infections. The RIG-I protein acts as a sensor for viral dsRNA, triggering interferon production through K63-linked poly-ubiquitin ch...

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Bibliographic Details
Main Author: Muhammad, Suleman (author)
Other Authors: Sayaf, Abrar Mohammad (author), Khan, Abbas (author), Khan, Salman Ali (author), Albekairi, Norah A. (author), Alshammari, Abdulrahman (author), Agouni, Abdelali (author), Yassine, Hadi M. (author), Crovella, Sergio (author)
Format: article
Published: 2024
Subjects:
Influenza A NS1
TRIM25
Molecular dynamics
Natural Products Databases
Host immunity
Online Access:http://dx.doi.org/10.1016/j.jiph.2024.05.005
https://www.sciencedirect.com/science/article/pii/S187603412400145X
http://hdl.handle.net/10576/59371
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http://dx.doi.org/10.1016/j.jiph.2024.05.005
https://www.sciencedirect.com/science/article/pii/S187603412400145X
http://hdl.handle.net/10576/59371

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