Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats

Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats

Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. The protective effect of ESA against diabetic retinopathy is not well-investigated and was the core objective of this study. In addition, we tested if such protection involves the activation of Nrf2...

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Bibliographic Details
Main Author: Nasser A., Alsabaani (author)
Other Authors: Amawi, Kawther (author), Eleawa, Samy M. (author), Nabeel Ibrahim, Wisam (author), Aldhaban, Walid (author), Alaraj, Ahmad Mohammad (author), Alkhalaf, Badr (author), Sami, Waqas (author), Alshaikhli, Hisham (author), Alkhateeb, Mahmoud A. (author)
Format: article
Published: 2024
Subjects:
Esculeoside A
Tomato
Diabetes mellitus
Retina
Nrf2
REDD1
Online Access:http://dx.doi.org/10.1016/j.biopha.2024.116461
https://www.sciencedirect.com/science/article/pii/S0753332224003457
http://hdl.handle.net/10576/55238
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