Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review
Purpose Infantile hemangiomas (IH) are the most common benign vascular tumors of infancy. Ocular complications due to orbital IH include strabismal, deprivational, or anisometropic astigmatism, and visual loss secondary to amblyopia. Observations We report a case of a two-month-old female infant wit...
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| مؤلفون آخرون: | , , , , |
| التنسيق: | article |
| منشور في: |
2021
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://dx.doi.org/10.1016/j.ajoc.2021.101095 https://www.sciencedirect.com/science/article/pii/S2451993621001043?v=s5 http://hdl.handle.net/10576/18290 |
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| _version_ | 1857415086774157312 |
|---|---|
| author | Denisa, Zvizdic |
| author2 | Bulja, Deniz Sidran, Amila Skenderi, Faruk Zvizdic, Zlatan Vranic, Semir |
| author2_role | author author author author author |
| author_facet | Denisa, Zvizdic Bulja, Deniz Sidran, Amila Skenderi, Faruk Zvizdic, Zlatan Vranic, Semir |
| author_role | author |
| dc.creator.none.fl_str_mv | Denisa, Zvizdic Bulja, Deniz Sidran, Amila Skenderi, Faruk Zvizdic, Zlatan Vranic, Semir |
| dc.date.none.fl_str_mv | 2021-04-20T10:11:46Z 2021-04-16 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://dx.doi.org/10.1016/j.ajoc.2021.101095 24519936 https://www.sciencedirect.com/science/article/pii/S2451993621001043?v=s5 http://hdl.handle.net/10576/18290 |
| dc.language.none.fl_str_mv | en |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Hemangioma Benign tumors Infants Treatment Propranolol |
| dc.title.none.fl_str_mv | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Purpose Infantile hemangiomas (IH) are the most common benign vascular tumors of infancy. Ocular complications due to orbital IH include strabismal, deprivational, or anisometropic astigmatism, and visual loss secondary to amblyopia. Observations We report a case of a two-month-old female infant with a severe deep orbital IH. The diagnosis was established by clinical examination and magnetic resonance imaging (MRI). The patient was treated with oral propranolol for six months. Complete tumor regression was observed clinically and by MRI following the treatment. The patient showed no adverse effects or tumor recurrence at the 14-month follow-up. Conclusions and Importance: Despite its benign nature, periorbital IH requires a rapid diagnosis and prompt treatment to prevent vision loss, particularly in infants. Our case confirms that oral propranolol may be regarded as a safe drug for periorbital IH with an excellent outcome. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | qu_dce51bad8131b44de66f05b8ae8d70dc |
| identifier_str_mv | 24519936 |
| language_invalid_str_mv | en |
| network_acronym_str | qu |
| network_name_str | Qatar University repository |
| oai_identifier_str | oai:qspace.qu.edu.qa:10576/18290 |
| publishDate | 2021 |
| publisher.none.fl_str_mv | Elsevier |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| spelling | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature reviewDenisa, ZvizdicBulja, DenizSidran, AmilaSkenderi, FarukZvizdic, ZlatanVranic, SemirHemangiomaBenign tumorsInfantsTreatmentPropranololPurpose Infantile hemangiomas (IH) are the most common benign vascular tumors of infancy. Ocular complications due to orbital IH include strabismal, deprivational, or anisometropic astigmatism, and visual loss secondary to amblyopia. Observations We report a case of a two-month-old female infant with a severe deep orbital IH. The diagnosis was established by clinical examination and magnetic resonance imaging (MRI). The patient was treated with oral propranolol for six months. Complete tumor regression was observed clinically and by MRI following the treatment. The patient showed no adverse effects or tumor recurrence at the 14-month follow-up. Conclusions and Importance: Despite its benign nature, periorbital IH requires a rapid diagnosis and prompt treatment to prevent vision loss, particularly in infants. Our case confirms that oral propranolol may be regarded as a safe drug for periorbital IH with an excellent outcome.Elsevier2021-04-20T10:11:46Z2021-04-16Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.ajoc.2021.10109524519936https://www.sciencedirect.com/science/article/pii/S2451993621001043?v=s5http://hdl.handle.net/10576/18290enhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/182902024-07-23T11:23:35Z |
| spellingShingle | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review Denisa, Zvizdic Hemangioma Benign tumors Infants Treatment Propranolol |
| status_str | publishedVersion |
| title | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| title_full | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| title_fullStr | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| title_full_unstemmed | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| title_short | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| title_sort | Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review |
| topic | Hemangioma Benign tumors Infants Treatment Propranolol |
| url | http://dx.doi.org/10.1016/j.ajoc.2021.101095 https://www.sciencedirect.com/science/article/pii/S2451993621001043?v=s5 http://hdl.handle.net/10576/18290 |