The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports

The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports

The 3,4-methylenedioxy-alpha-pyrrolidinohexanophenone (MDPHP) is a synthetic cathinone closely related to 3,4-methylenedioxypyrovalerone (MDPV), one of the most common synthetic cathinones present in the “bath salts”. MDPHP has recently gained attention due to increasing seizures and involvement in...

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Bibliographic Details
Main Author: Marta, Bassi (author)
Other Authors: Bilel, Sabrine (author), Tirri, Micaela (author), Corli, Giorgia (author), Di Rosa, Fabiana (author), Gregori, Adolfo (author), Alkilany, Alaaldin M. (author), Rachid, Ousama (author), Roda, Elisa (author), De Luca, Fabrizio (author), Papa, Pietro (author), Buscaglia, Eleonora (author), Zauli, Giorgio (author), Locatelli, Carlo Alessandro (author), Marti, Matteo (author)
Format: article
Published: 2024
Subjects:
3,4-methylenedioxy-alpha-pyrrolidinohexanophenone
3,4-methylenedioxypyrovalerone
Synthetic cathinone
Behaviour
Aggressivity
Cardiovascular effect
ADMET prediction
Human intoxication
Online Access:http://dx.doi.org/10.1016/j.neuro.2024.06.014
https://www.sciencedirect.com/science/article/pii/S0161813X2400069X
http://hdl.handle.net/10576/59331
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