Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar
BackgroundSome studies have reported that influenza vaccination is associated with lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) morbidity and mortality. This study aims to estimate effectiveness of influenza vaccinati...
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| مؤلفون آخرون: | , , , , , , , , , , , , |
| التنسيق: | article |
| منشور في: |
2023
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://dx.doi.org/10.1016/j.jiph.2022.12.016 https://www.sciencedirect.com/science/article/pii/S1876034122003665 http://hdl.handle.net/10576/42680 |
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| _version_ | 1857415084347752448 |
|---|---|
| author | Elias, Tayar |
| author2 | Abdeen, Sami Abed Alah, Muna Chemaitelly, Hiam Bougmiza, Iheb Ayoub, Houssein H. Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Al-Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto Abu-Raddad, Laith J. Al-Khal, Abdullatif |
| author2_role | author author author author author author author author author author author author author |
| author_facet | Elias, Tayar Abdeen, Sami Abed Alah, Muna Chemaitelly, Hiam Bougmiza, Iheb Ayoub, Houssein H. Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Al-Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto Abu-Raddad, Laith J. Al-Khal, Abdullatif |
| author_role | author |
| dc.creator.none.fl_str_mv | Elias, Tayar Abdeen, Sami Abed Alah, Muna Chemaitelly, Hiam Bougmiza, Iheb Ayoub, Houssein H. Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Al-Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto Abu-Raddad, Laith J. Al-Khal, Abdullatif |
| dc.date.none.fl_str_mv | 2023-05-14T07:12:55Z 2023-02-28 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://dx.doi.org/10.1016/j.jiph.2022.12.016 Tayar, E., Abdeen, S., Alah, M. A., Chemaitelly, H., Bougmiza, I., Ayoub, H. H., ... & Al-Khal, A. (2023). Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar. Journal of Infection and Public Health, 16(2), 250-256. 1876-0341 1876-035X https://www.sciencedirect.com/science/article/pii/S1876034122003665 http://hdl.handle.net/10576/42680 250-256 2 16 |
| dc.language.none.fl_str_mv | en |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Influenza COVID-19 Vaccine Case-control Immunity Epidemiology |
| dc.title.none.fl_str_mv | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | BackgroundSome studies have reported that influenza vaccination is associated with lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) morbidity and mortality. This study aims to estimate effectiveness of influenza vaccination, using Abbott’s quadrivalent Influvac Tetra vaccine, against SARS-CoV-2 infection and against severe COVID-19. MethodsThis matched, test-negative, case-control study was implemented on a population of 30,774 healthcare workers (HCWs) in Qatar during the 2020 annual influenza vaccination campaign, September 17, 2020-December 31, 2020, before introduction of COVID-19 vaccination. ResultsOf 30,774 HCWs, 576 with PCR-positive tests and 10,033 with exclusively PCR-negative tests were eligible for inclusion in the study. Matching by sex, age, nationality, reason for PCR testing, and PCR test date yielded 518 cases matched to 2058 controls. Median duration between influenza vaccination and the PCR test was 43 days (IQR, 29–62). Estimated effectiveness of influenza vaccination against SARS-CoV-2 infection> 14 days after receiving the vaccine was 29.7% (95% CI: 5.5–47.7%). Estimated effectiveness of influenza vaccination against severe, critical, or fatal COVID-19 was 88.9% (95% CI: 4.1–98.7%). Sensitivity analyses confirmed the main analysis results. ConclusionsRecent influenza vaccination is associated with a significant reduction in the risk of SARS-CoV-2 infection and COVID-19 severity. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | qu_f69faf31cbc787c66908f0a6bbda4250 |
| identifier_str_mv | Tayar, E., Abdeen, S., Alah, M. A., Chemaitelly, H., Bougmiza, I., Ayoub, H. H., ... & Al-Khal, A. (2023). Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar. Journal of Infection and Public Health, 16(2), 250-256. 1876-0341 1876-035X 250-256 2 16 |
| language_invalid_str_mv | en |
| network_acronym_str | qu |
| network_name_str | Qatar University repository |
| oai_identifier_str | oai:qspace.qu.edu.qa:10576/42680 |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Elsevier |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| spelling | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in QatarElias, TayarAbdeen, SamiAbed Alah, MunaChemaitelly, HiamBougmiza, IhebAyoub, Houssein H.Kaleeckal, Anvar HassanLatif, Ali NizarShaik, Riyazuddin MohammadAl-Romaihi, Hamad EidAl-Thani, Mohamed H.Bertollini, RobertoAbu-Raddad, Laith J.Al-Khal, AbdullatifInfluenzaCOVID-19VaccineCase-controlImmunityEpidemiologyBackgroundSome studies have reported that influenza vaccination is associated with lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) morbidity and mortality. This study aims to estimate effectiveness of influenza vaccination, using Abbott’s quadrivalent Influvac Tetra vaccine, against SARS-CoV-2 infection and against severe COVID-19. MethodsThis matched, test-negative, case-control study was implemented on a population of 30,774 healthcare workers (HCWs) in Qatar during the 2020 annual influenza vaccination campaign, September 17, 2020-December 31, 2020, before introduction of COVID-19 vaccination. ResultsOf 30,774 HCWs, 576 with PCR-positive tests and 10,033 with exclusively PCR-negative tests were eligible for inclusion in the study. Matching by sex, age, nationality, reason for PCR testing, and PCR test date yielded 518 cases matched to 2058 controls. Median duration between influenza vaccination and the PCR test was 43 days (IQR, 29–62). Estimated effectiveness of influenza vaccination against SARS-CoV-2 infection> 14 days after receiving the vaccine was 29.7% (95% CI: 5.5–47.7%). Estimated effectiveness of influenza vaccination against severe, critical, or fatal COVID-19 was 88.9% (95% CI: 4.1–98.7%). Sensitivity analyses confirmed the main analysis results. ConclusionsRecent influenza vaccination is associated with a significant reduction in the risk of SARS-CoV-2 infection and COVID-19 severity.Elsevier2023-05-14T07:12:55Z2023-02-28Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.jiph.2022.12.016Tayar, E., Abdeen, S., Alah, M. A., Chemaitelly, H., Bougmiza, I., Ayoub, H. H., ... & Al-Khal, A. (2023). Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar. Journal of Infection and Public Health, 16(2), 250-256.1876-03411876-035Xhttps://www.sciencedirect.com/science/article/pii/S1876034122003665http://hdl.handle.net/10576/42680250-256216enhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:qspace.qu.edu.qa:10576/426802024-07-23T13:53:12Z |
| spellingShingle | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar Elias, Tayar Influenza COVID-19 Vaccine Case-control Immunity Epidemiology |
| status_str | publishedVersion |
| title | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| title_full | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| title_fullStr | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| title_full_unstemmed | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| title_short | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| title_sort | Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar |
| topic | Influenza COVID-19 Vaccine Case-control Immunity Epidemiology |
| url | http://dx.doi.org/10.1016/j.jiph.2022.12.016 https://www.sciencedirect.com/science/article/pii/S1876034122003665 http://hdl.handle.net/10576/42680 |