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The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms
منشور في 2008"…Conversely, treatment with GW9662 decreased TG mass and impaired adiponectin oligomer assembly but did not decrease total adiponectin mass. …"
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
منشور في 2024"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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Integration of Wind Catchers in Modern Residential Buildings in the UAE as a Means of Providing Thermal Comfort
منشور في 2014"…This research is an evaluation of the effectiveness of wind catchers as means of providing thermal comfort for modern residential buildings in the hot arid climates in the UAE. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. By elucidating a mechanistic basis for the increased affinity of the N501Y mutant S1-RBD for ACE2, we believe that the results presented here will aid in developing therapeutic strategies against SARS-CoV-2 including designing of therapeutic agents targeting the ACE2-S1-RBD interaction.…"
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Tranexamic Acid Application in Facial Aesthetic Surgery: An Umbrella Review
منشور في 2024"…<p dir="ltr">Tranexamic acid (TXA) is an antifibrinolytic agent that is considered as one of the latest interventions currently being investigated in the field of facial aesthetic surgeries, as it is predicted to be effective in reducing intraoperative and postoperative complications of facial aesthetic surgeries. …"
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Solubilization of Protein Aggregates by the Acid Stress Chaperones HdeA and HdeB
منشور في 2008"…Moreover, a marked decrease in the exposed hydrophobicity of aggregated proteins in the presence of HdeA and HdeB was revealed by 1,1′-bis(4-anilino)naphtalene-5,5′-disulfonic acid binding experiments. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Effects of electrolytes and suwannee river humic acid on the aggregation behavior of silicon nanoparticles
منشور في 2017"…The aggregation rates in the presence of SRHA were higher than that in the absence of SRHA at the same Ca2+ concentrations and the critical coagulation concentrations (CCC) decreased from 0.4 M to 0.1 M. The enhanced aggregation was attributed to bridging caused by Ca2+ and SRHA.…"
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n-Hexadecane Fuel for a Phosphoric Acid Direct Hydrocarbon Fuel Cell
منشور في 2015"…The objective of this work was to examine fuel cells as a possible alternative to the diesel fuel engines currently used in railway locomotives, thereby decreasing air emissions from the railway transportation sector. …"
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …"
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Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications
منشور في 2019"…Increasing the polyphenol concentration caused the tensile strength and Young’s modulus to decrease. The SEM graphs indicated a decrease in fibre diameter with increasing DP content. …"
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Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
منشور في 2018"…There was a significant decrease in PTEN activity as evident by a rise in the phosphorylated form of this protein. …"
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Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
منشور في 2019"…Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …"
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
منشور في 2024"…Study objectiveTraumatic injury causes a significant number of deaths due to bleeding. Tranexamic acid (TXA), an antifibrinolytic agent, can reduce bleeding in traumatic injuries and potentially enhance outcomes. …"
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Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA
منشور في 2022"…Driven by the rising deployment of deep reinforcement learning (DRL) techniques that are capable of coping with solving non-convex optimization problems, we employ DRL to predict and optimally tune the IRS phase shift matrices. …"
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Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
منشور في 2023"…Treatment with 20mg/Kg Cannabis oil caused a significant increase in body weight compared to the Folic acid treated group. In addition, a significant decrease in serum creatinine was observed in groups receiving cannabis extract at the doses of 5 and 10 mg/kg. …"
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masterThesis