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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. Decreased whole body exposure to MG-derived AGEs may be linked to increased weight specific physical activity of HSA-mUCP1 mice. …"
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article -
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. Decreased whole body exposure to MG-derived AGEs may be linked to increased weight specific physical activity of HSA-mUCP1 mice. …"
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Integration of Wind Catchers in Modern Residential Buildings in the UAE as a Means of Providing Thermal Comfort
منشور في 2014"…This research is an evaluation of the effectiveness of wind catchers as means of providing thermal comfort for modern residential buildings in the hot arid climates in the UAE. …"
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Sequential therapy in patients receiving Fluoroquinolones at the American University of Beirut Medical Center. (c2001)
منشور في 2001"…Date of switch (if applicable), oral antibiotic chosen, mean time to switch, mean hospital duration, and mean treatment duration were also recorded. …"
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masterThesis -
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Empiric antibiotic therapy of community-acquired Pneumonia at the American University of Beirut Medical Center. (c2001)
منشور في 2001"…Special attention should be given to decrease hospitalization rate, to preserve fluoroquinolones, and to improve microbiological studies outcome.…"
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masterThesis -
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Two-Surgeon Technique for Hepatic Parenchymal Transection of the Noncirrhotic Liver Using Saline-Linked Cautery and Ultrasonic Dissection
منشور في 2005"…To date, no single instrument has been designed that addresses both of these tasks. Saline-linked cautery is now widely used in liver surgery and is reported to decrease blood loss during liver transection, but data on its exact benefits are lacking. …"
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Dynamic Analysis of Flexible Mechanisms with Clearance
منشور في 2016احصل على النص الكامل
doctoralThesis -
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Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …"
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
منشور في 2021"…Purpose Establishing the reliability of a new method to check the mean retinal and choroidal reflectivity and using it to find retinal and choroid changes in amblyopia. …"
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Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…</p><h3>Objective </h3><p dir="ltr">The objective of this study was to determine the prevalence of polypharmacy (≥ 5 drugs) and its association with non-communicable diseases (NCDs) in elderly (≥65 years) Qatari patients attending Primary Healthcare (PHC) centers in Qatar. </p><h3>Methods </h3><p dir="ltr">A retrospective cross-sectional analysis was conducted using the Electronic Medical Record (EMR) database of all PHC centers in Qatar for six months (April-September 2017). …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
منشور في 2021"…MG activated the intrinsic pathway of apoptosis, with decrease of mitochondrial and spliceosomal proteins. …"