The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…These results reiterate the decisive role of 5-Aza-CdR in lung cancer treatment since it induces the epigenetic regulation of NY-ESO-1 antigen, inhibits cell proliferation, increases apoptosis, and decreases invasiveness.…"

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar حسب Doua Abdelrahman (17280667)

"…Results: Only 1.4% (70/5026) of the samples had detectible B19V DNA in their blood. B19V DNA prevalence statistically decreased with age (p = 0.03). …"

Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature حسب Henry C. Ezechukwu (13253406)

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

"…Using a systematic review of the epidemiological literature and a newly developed meta-regression tool (meta-regression: Bayesian, regularised, trimmed), we derived disease-specific, non-parametric exposure–response curves to estimate relative risk as a function of PM2·5 concentration. …"
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…<p dir="ltr">Triple-negative breast cancer (TNBC) accounts for ~15–20% of breast cancer (BC) and has a higher rate of early relapse and mortality compared to other subtypes. The Chemokine (C-C motif) ligand 5 (CCL5) and its signaling pathway have been linked to TNBC. …"

Non-diabetic ketoacidosis secondary to primary hyperthyroidism حسب Abdulrahman F. Al-Mashdali (17148316)

"…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …"

Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic حسب Turki, O.

"…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…"
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Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function حسب Julien Bricambert (19738237)

"…Similarly, hypoxia hampered total Hdac activity and reduced the expression of <i>Hdac5</i> and <i>Hdac6</i> in 3T3-L1 adipocytes. The decrease of both <i>Hdac5</i> and <i>Hdac6</i> by hypoxia was associated with altered expression of adipokines and of the inducible cAMP early repressor (Icer), a key repressor that is defective in human and mice obesity. …"

A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor حسب Anupriya M. Geethakumari (17052375)

"…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M^pro activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M^pro and functional genomics application to determine the effect of sequence variation in M^pro.…"

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... حسب Katherine R Paulson (8674293)

Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability حسب Mohammad Meraj (16855401)

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas حسب Abu Saleh Md Moin (6189512)

"…CPHN cells represent a non-replicative pool of endocrine precursor cells, a proportion of which are likely fated to become beta-cells.…"

Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution حسب Khuram Shahzad (575887)

Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA حسب Muhammad Shehab (16904880)

Determinants of Non-Performing Loans in the State of Qatar With Special References to Small and Medium Enterprises حسب Muhannad Abdullah Almuraikhi (21547001)

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans حسب Kevin S. Chen (9201767)

"…Together with artificial intelligence-driven in silico and in vitro screening, this C. elegans model identified five compounds that reduced motor dysfunction induced by α-synuclein. …"

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? حسب Wahiba Elhag (5245547)

"…Mean HbA1c significantly decreased from 8.1%preop to 6.77%_{year 9}. …"

Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students حسب Monoem Haddad (5345357)

"…In the second regression analysis, controlling for age, body mass, and BMI, the regression coefficients associated with height (B = −1.692, 95% CI [−3.115, −0.269], p < 0.05] and body fat percentage (B = 0.529, 95% CI [0.075, 0.983], p < 0.05) indicated that with each additional unit of height or body fat percentage, the CMJ AI decreased by 1.692 units and increased by 0.529 units. …"