Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy . حسب Djouhri, Laiche

"…However, DPNP is believed to be due partly to abnormal hyperexcitability of dorsal root ganglion (DRG) neurons, but the relative contributions of specific functional subtypes remain largely unknown. Here, using the strepotozotocin (STZ) rat model of DPNP induced by a STZ injection (60 mg/kg, i.p), and intracellular recordings of action potentials (APs) from DRG neurons in anesthetized rats, we examined electrophysiological changes in C-and Aβ-nociceptive and Aβ-low threshold mechanoreceptive (LTM) neurons that may contribute to DPNP. …"
احصل على النص الكامل
احصل على النص الكامل

Differential oxidative stress responses to methanol in intraperitoneally exposed rats: Ameliorative effects of Opuntia vulgaris fruit extract حسب Saoudi, Mongi

"…Methanol intoxication significantly increased hepatic and renal lipid peroxidation evaluated by thiobarbituric acid reactive substances in treated rats as compared to controls. However, hepatic and renal antioxidant enzymes namely superoxide dismutase, catalase, and glutathione peroxidase were significantly decreased in methanol-treated animals as compared to controls. …"
احصل على النص الكامل
احصل على النص الكامل

Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy حسب Laiche, Djouhri

"…In the present immunohistochemical study, we sought to determine whether Kv7.2 and/or Kv7.5 channel expression is altered in DRG neurons in STZ rats. We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish. حسب Benslimane, Fatiha M

"…While clinical echocardiography platforms can be used for relatively large animals such as pigs and rats, specialized systems are needed for smaller species. …"
احصل على النص الكامل
احصل على النص الكامل

The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio... حسب Zakaria, El Rasheid

"…In all four groups, class IV hemorrhagic shock remarkably decreased hemoglobin, hematocrit and produced a metabolic acidosis characterized by low pH, PCO2, HCO3, TCO2 and an increase in the base deficit as compared with the baseline pre-hemorrhage levels. …"
احصل على النص الكامل
احصل على النص الكامل