The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008) حسب Maalouf, Katia E.

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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells حسب Nouralhuda Alateyah (21363215)

"…TI significantly suppressed BC cell growth, inhibited migration and invasion and induced apoptosis. Interestingly, apoptosis was mediated by a significant loss of mutant p53 protein, and increased Bax/Bcl2 ratio. …"

β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo حسب Daaboul, Hamid E.

"…Papilloma incidence, yield and volume were monitored, and isolated papillomas were assessed for their pro/anti-apoptotic proteins and morphology. Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …"
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…With respect to the proteins studied, treatment with Urtica dioica extract significantly increased the expression of the pro-apoptotic protein Bax with concomitant decrease in the anti-apoptotic protein Bcl-2 expression. …"
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways حسب Daaboul, Hamid E.

"…Flow cytometry analysis revealed that 10 μg/ml HC increased the number of cells undergoing necrosis (18.05%) and late apoptosis (15.66%). At HC 25 μg/ml more cells shifted toward necrosis (58.01%) and late apoptosis (30.47%). …"
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis حسب Daaboul, Hamid E.

"…Papilloma yield, volume, histology, and mice weight and liver function were assessed. HC treatment decreased significantly cell survival (IC50 = 7 and IC90 = 40 μg/ml) and increased significantly cells undergoing late apoptosis and necrosis. …"
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Drug-free phototherapy of superficial tumors حسب Mehanna, Stephanie

"…After a 9-h exposure in vitro, the viability of Human Malignant Melanoma cells (A375) decreased by around 70%. Western blot analysis suggested an apoptotic cell death confirmed by the upregulation of Bax, cleaved PARP/caspase-3/8, cytochrome c, and t-bid. …"
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…"

The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells حسب Fayad, Christelle

"…Determination of the octanol-water partition coefficient (log P) of the various complexes revealed that C3 is the most lipophilic which justifies its high cellular uptake and high cytotoxicity. …"
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The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells حسب Fayad, Christelle

"…Determination of the octanol–water partition coefficient (log P) revealed that C3 was the only lipophilic complex (log P = 0.42). …"
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Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells حسب Sara Al Tamimi (9692615)

"…Furthermore, we observed the cell death pathway by the apoptosis marker Annexin-V which showed non-significant results, while the exposure of AgCu-NP in MCF-7 cells leads to toxicity and also caused significant increase in MMP-9 level, which suggests the cell death may be associated with other pathways such as autophagy and oxidative stress related.…"