Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Hematoxylin and eosin staining and Sirius red staining were performed to identify bone formation in vivo. Results. Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitness in US Adults حسب Vijay Ganji (8710491)

Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice حسب Charlotte Rinne (18766966)

"…Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content حسب Haissam Abou-Saleh (497840)

"…At the end of dietary intervention, bone resorption markers in serum and inflammatory markers in bone marrow and splenocytes and inflammatory signaling pathways in the bone marrow were analyzed. …"

Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells حسب Tahir Abdulrehman (8697696)

"…In addressing the issue, this study deals with the targeting of silver-copper-boron (ACB) nanoparticles to infected osteoblasts, which could decrease systemic toxicity and form the basis of targeting specific markers expressed in bone infections.…"

Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines حسب Najlah, Mohammad

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The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells حسب Ibraheem M. Attafi (14151735)

Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan, Sirin

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Al-Hamdani, Mohammed

"…Background: Bone mineral density (BMD) is an indicator of bone health that predicts future bone fractures. …"
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Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Mohammed Al-Hamdani (16962702)

"…<h3>Background</h3><p dir="ltr">Bone mineral density (BMD) is an indicator of bone health that predicts future bone fractures. …"

An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health حسب Belqes Alsadi (18695031)

"…We observed that bone area, bone mineral content, and bone mineral density were slightly lower in the Diabetes group across almost all body parts, but the difference against the control group was not statistically significant except in T12, troch and trunk area. …"

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling حسب Sabah Akhtar (5809925)

"…In this study, we aimed to investigate the potential anti-proliferative and pro-apoptotic activities of SNG in a panel of MM cell lines (U266, IM9, MM1S, and RPMI-8226). SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …"

The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading حسب Hozhabr Mozafari (18891892)

"…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …"

Innovative strategies to reduce traffic related injuries and deaths in youth حسب Joanne Banfield (19794507)

"…(Prevent Alcohol and Risk-Related Trauma in Youth) Program is one of those programs. …"

Impact of severe hypoglycemia on the heat shock and related protein response حسب Alexander S. Atkin (18520107)

"…Our hypothesis was that hypoglycemia-induced heat shock and related protein changes would be amplified in type 2 diabetes (T2D). …"

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

"…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"

Epidemiological and clinical characteristics of fall-related injuries: a retrospective study حسب Ahammed Mekkodathil (4578838)

"…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …"