The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues حسب Naushad Ahmad Khan (6406973)

"…The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …"

Optimizing clopidogrel dose response حسب Saab, Yolande B.

"…Results The study results show that all patients under clopidogrel treatment, whose genotypes are different from *1*1, and concomitantly taking other drugs metabolized by CYP2C19 require clopidogrel dose adjustment. To get a therapeutic effect and avoid adverse drug reactions, therapeutic dose of 75 mg clopidogrel, for example, should be lowered to 6 mg or increased to 215 mg in patients with different genotypes. …"
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Development of image quality related reference doses called acceptable quality doses (AQD) in paediatric CT exams in Qatar حسب Mohammad Hassan Kharita (14158812)

"…<h2>Objectives</h2> <p>To describe first experience of integrating assessment of image quality in paediatric X-ray computed tomography (CT) with analysis of the radiation dose indices to develop reference doses called acceptable quality dose (AQD).…"

Improvement of Dialysis Dosing Using Big Data Analytics حسب Mumtaz, Syeda Leena

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Regression Analysis between the Different Breast Dose Quantities Reported in Digital Mammography and Patient Age, Breast Thickness, and Acquisition Parameters حسب Dhou, Salam

"…Screening mammography is considered the primary imaging modality for the early detection of breast cancer. The radiation dose from mammography increases the patients’ risk of radiation-induced cancer. …"
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The effect of vancomycin doses greater than 2 grams on serum creatinine and vancomycin trough levels حسب Mansour, Hanine

"…Conclusion: The use of doses greater than 2 grams of IV vancomycin did not show a statistically significant increase in serum creatinine. …"
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The Effect of Different Doses of Intravenous Dexmedetomidine on the Properties of Subarachnoid Blockade: A Systematic Review and Meta-Analysis حسب Mohammad K Al Nobani (16561248)

"…Dexmedetomidine-related side effects were higher in patients receiving larger doses; the incidence of bradycardia was higher (OR=3.53, P<0.001) and incidence of hypotension showed a 1.29 fold increase when compared to the control group (P=0.065).…"

Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats حسب Zeeni, Nadine

"…In addition, T. porrifolius extract preload produced a dose dependent decrease in food intake observed over 24 h. …"
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Size Increment During Surveillance in Papillary Thyroid Cancer: Evidence Synthesis and Dose–Response Meta‐Analysis حسب Mohamed Badie Ahmed (10223510)

"…</p><h3>Methods</h3><p dir="ltr">A dose–response meta‐analysis was conducted using the robust error meta‐regression method, using time as the “dose” and cumulative progression (%) was assessed. …"

Evolution of gastroesophageal reflux disease symptoms after bariatric surgery: A dose–response meta-analysis حسب Abdel-Naser Elzouki (9376853)

"…<h3>Background</h3><p dir="ltr">Obesity is associated with increased prevalence of gastroesophageal reflux disease, with recent reports suggesting improvement in gastroesophageal reflux disease symptoms and weight loss following bariatric surgical intervention. …"

Comparative effectiveness of one versus two doses of COVID-19 vaccines in Qatar: Evidence of converging protection over time حسب Hiam Chemaitelly (439114)

"…In contrast to the gradual buildup of protection against infection, single-dose effectiveness against severe, critical, or fatal COVID-19 increased rapidly for all three vaccines, exceeding 85 % by day 21 and closely matching the protection achieved after two doses.…"

Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro حسب Khalife, Rana

"…Topotecan, a topoisomerase I inhibitor, is an anticancer drug widely used in the therapy of lung, ovarian, colorectal, and breast adenocarcinoma. Due to the primary dose-limiting toxicity of topotecan, which is myelosuppressive, it is necessary to identify other chemotherapeutic agents that can work synergistically with topotecan to increase its efficacy and limit its toxicity. …"
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The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women حسب Thozhukat Sathyapalan (704787)

"…</p><h3>Conclusion</h3><p dir="ltr">Soy isoflavones transiently increased rT3 levels within 3 months though reverted to baseline at 6 months. …"

A cost-effectiveness analysis for high versus standard (low) dose caffeine for the treatment of apnea in neonatal intensive care unit حسب Eilan Al-Hersh (21841532)

"…Recent literature supported higher maintenance doses of caffeine, indicating benefits. This study evaluated the cost-effectiveness of high maintenance dose (HD) versus low maintenance dose (LD) caffeine for AOP in neonates.…"

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care حسب Ahmad Kloub (16855149)

"…We investigated whether switching from fixed-dose dalteparin to anti-Xa-guided enoxaparin prophylaxis reduces VTE without increasing the risk of bleeding among hospitalized trauma patients.…"

Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis حسب Ahmed Fouad Algendy (18102706)

"…At the same time, documented hypoglycemia was insignificantly higher (AOR 1.17, p= 0.444) with gliclazide MR compared to glimepiride. The low doses of both treatments did not show any SHEA cases, while the results with higher doses showed the same pattern of increased risk with gliclazide MR as the principle analysis. …"

Thermal profiles of amorphous solid dispersions (ASD) in 3D printed tablets by fused deposition modelling (FDM): Production of tunable tablet doses حسب Heba Iqbal (17337667)

"…Aptly, there was a 35% increase in solubility and a significant increase (<i>p</i> < 0.05) in dissolution rates of ibuprofen from 3D printed ASD tablets compared to printed tablets of pure ibuprofen. …"

The impact of automatic tube current modulation related settings of a modern GE CT scanner on image quality and patient dose; details do matter حسب Ioannis A. Tsalafoutas (14776939)

"…</p><h3>Conclusion</h3><p dir="ltr">SmartmA is a tool that if not properly used may increase the patient doses considerably. Therefore, its settings should be carefully adjusted for each preset different clinical protocol.…"

Assessment of water quality variations on pretreatment and environmental impacts of SWRO desalination حسب Abdulrahman Al-Kaabi (17075194)

First Case Report of Fulminant Hepatitis After Laparoscopic Sleeve Gastrectomy Associated with Concomitant Maximal Therapeutic Dose of Acetaminophen Use, Protein Calorie Malnutriti... حسب Alyaa Abusabeib (14151852)

"…<p>Nonalcoholic fatty liver disease (NAFLD) is increasingly being linked to obesity. Although laparoscopic sleeve gastrectomy (LSG) is effective for weight loss that can ultimately resolve NAFLD, an initial transient deterioration of liver functions could be observed during the first few months post-operatively, after which a subsequent improvement of the liver functions might occur. …"