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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Impact of Work-Life Balance on Female Employee Motivation
منشور في 2023"…The study has revealed a link between work-life balance and employee motivation, suggesting that businesses that prioritize work-life balance policies will likely experience better levels of employee engagement, Productivity, well-being, retention, and decreased levels of stress. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Effect of UV Ageing on the fatigue life of bulk polyethylene
منشور في 2018"…The results show an important decrease of the fatigue limit with increasing absorbed UV irradiation dose.…"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Innovative strategies to reduce traffic related injuries and deaths in youth
منشور في 2015"…(Prevent Alcohol and Risk-Related Trauma in Youth) Program is one of those programs. …"
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The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading
منشور في 2017"…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …"
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Impact of severe hypoglycemia on the heat shock and related protein response
منشور في 2021"…Our hypothesis was that hypoglycemia-induced heat shock and related protein changes would be amplified in type 2 diabetes (T2D). …"
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Impact of Life-coaching on Students' Wellbeing and Engagement Levels in a Preparatory School in Qatar
منشور في 2019"…Both groups showed a decrease in satisfaction with life as well as most of the personality traits of the period of the school year. …"
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
منشور في 2023"…This thesis explores the relationship between living alone, loneliness, and quality of life (QoL) in elderly Europeans. This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …"
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Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …"
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The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
منشور في 2023"…<p dir="ltr">1p32.3 microdeletion/duplication is implicated in many neurodevelopmental disorders-like phenotypes such as developmental delay, intellectual disability, autism, macro/microcephaly, and dysmorphic features. …"
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
منشور في 2025"…Studies have shown that semaglutide reduced fat mass, particularly visceral fat, while preserving lean muscle mass, as the proportion relative to total body mass decreased by 3.5% and 2.0% for total and visceral fat mass, respectively, while it increased by 3.0% for lean body mass. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity
منشور في 2024"…The RCP was the benchmark for determining the relative intensity in the step tests among two conditions. …"
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Life cycle assessment of binary recycled ceramic tile and recycled brick waste-based geopolymers
منشور في 2022"…<p dir="ltr">This paper consists of a life cycle assessment (LCA) analysis on an experimental study to produce recycled brick waste (RBW) and recycled ceramic tile (RCT) based geopolymers. …"
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
منشور في 2023"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"