Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitness in US Adults حسب Vijay Ganji (8710491)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"

Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan, Sirin

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure حسب Mineko Baba (19774386)

"…<p dir="ltr">For the last fourteen years in Japan, casualties due to traffic collisions have decreased. There were 9,073 traffic fatalities in 2000 and 4,113 in 2014. …"

The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study حسب Aksam Yassin (14779204)

"…In this single-centre, cumulative, prospective, registry study, 321 hypogonadal men (mean age: 58.9 years) received testosterone undecanoate injections in 12-week intervals for up to 12 years. …"

Innovative strategies to reduce traffic related injuries and deaths in youth حسب Joanne Banfield (19794507)

"…(Prevent Alcohol and Risk-Related Trauma in Youth) Program is one of those programs. …"

The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading حسب Hozhabr Mozafari (18891892)

"…At the first step, experimental tests were carried out on a corrugated tube with three corrugations (two inner and one outer) and a tube without corrugation. After that, a finite element model was developed by means of ABAQUS software in order to study the effect of corrugation number on crushing properties of thin-walled tubes. …"

Impact of severe hypoglycemia on the heat shock and related protein response حسب Alexander S. Atkin (18520107)

"…Our hypothesis was that hypoglycemia-induced heat shock and related protein changes would be amplified in type 2 diabetes (T2D). …"

Epidemiological and clinical characteristics of fall-related injuries: a retrospective study حسب Ahammed Mekkodathil (4578838)

"…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …"

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> حسب Safa Salim (9186786)

"…Moreover, Ssdp overexpression led to differential changes in synaptic density in specific brain regions. We observed decreased levels of armadillo in the heads of Ssdp overexpressing flies, as well as a decrease in armadillo and wingless expression in the larval wing discs, implicating the involvement of the canonical Wnt signaling pathway in Ssdp functionality. …"

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. حسب Sara, Sokary

"…Studies have shown that semaglutide reduced fat mass, particularly visceral fat, while preserving lean muscle mass, as the proportion relative to total body mass decreased by 3.5% and 2.0% for total and visceral fat mass, respectively, while it increased by 3.0% for lean body mass. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan Sirin (14603304)

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"

Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity حسب Dania Nazeeh Ibrahim (21547487)

"…The RCP was the benchmark for determining the relative intensity in the step tests among two conditions. …"

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"

One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes حسب Goran Petrovski (129836)

Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia حسب Abu Saleh Md Moin (6189512)

"…At hypoglycemia, UBE2N, STIP1, and UBE2L3 increased (all p < 0.05), whilst TLR4:MD-2 and HSPA8 decreased (p < 0.05) in T2D versus baseline. In follow-up after hypoglycemia, HSPs normalized to baseline by 24 h, except UBE2L3 (p < 0.05), which was decreased in controls versus baseline. …"

Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States حسب Abdul Ahad (545575)