Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"

Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles حسب Mariem Chamakh (14150481)

"…<p dir="ltr">Electrospinning technique was employed to fabricate composite nanofibers/nanoparticles of sulfonated polyether ether ketone, polyvinylpyrrolidone, and ruthenium oxide (sPEEK/PVP/RuO₂). The samples were synthesized with different concentrations of hydrous ruthenium chloride of 2 wt%, 5 wt%, and 10 wt%, and then annealed at a temperature of 300 °C for 4 h to form the ruthenium oxide nanoparticles. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"

Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan, Sirin

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading حسب Hozhabr Mozafari (18891892)

"…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …"

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. حسب Sara, Sokary

"…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of -0.16 mmol/L and -0.48 mmol/L, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan Sirin (14603304)

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> حسب Safa Salim (9186786)

"…<p dir="ltr">1p32.3 microdeletion/duplication is implicated in many neurodevelopmental disorders-like phenotypes such as developmental delay, intellectual disability, autism, macro/microcephaly, and dysmorphic features. …"

Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload حسب Naila Rabbani (291722)

"…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …"

The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

Exploring beyond numeric weight loss: The metabolic effects of semaglutide حسب Sara Sokary (17337724)

"…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of −0.16 mmol/L and −0.48 mmol/L, respectively. …"

Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes حسب Roland E Allen (19187023)

"…I.e., the largest possible decrease in glucose predicted by the model is smaller than reported decreases, and the model predicts no decrease whatsoever in glucose ×insulin, in contrast to large observed decreases in homeostatic model assessment insulin resistance (HOMA-IR). …"

Evidence-based safety education and training for traffic injury prevention حسب Abbas Motevalian (338825)

"…Review of the systematic reviews show that education only interventions are rarely effective on prevention of road traffic crashes. Except for some interventions like post-license driver education which has strong evidence based on large number of participants, in most of the subject interventions more rigorous investigation is needed especially in low- and middle- income countries.…"

Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review حسب Maged S. Alhammadi (14150757)

"…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …"

Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study حسب Husham Abdelrahman (768893)

"…There was a significant decrease in the trend of geriatric trauma over the years. …"

A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media حسب Shaheeda Marakkar Anangadan (19239607)

"…However, when accounting for leaching, which was significant in some organic media but expected to decrease with time, most organic media (SCG, date seeds, coco coir and bone) achieved around 80 % TOC removal. …"

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis حسب Charbel Abi Khalil (14150028)

"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"

Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar حسب Ayman Al-Dahshan (8962568)

"…Also, participants who used the internet for diet information a great deal were more likely to decrease the amount of sugary and fatty foods they ate compared to women who used the internet somewhat or very little (61.4, 45.2, and 18.2%, p < 0.001; respectively) and (50.9, 30.4, and 18.2%, p = 0.001; respectively).…"