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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Mutation of the two residues in NLuc revealed a decreased but stable activity of the R162A, but not Q32A, mutant NLuc in live cell and in vitro assays performed using lysates prepared from cells expressing the proteins and with the furimazine substrate. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Chemical biology approaches using small molecule inhibitors targeting specific signaling pathways are useful tools to dissect the molecular mechanisms governing stem cell differentiation and for their possible use in therapeutic interventions. …"
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
منشور في 2022"…This sentence previously stated:</p><p dir="ltr">“Representative trajectory movies of the 10 ns simulations were prepared from 5,000 trajectory snapshots (50 snapshots/ns) generated using VMD Movie Maker Tool (Humphrey et al., 1996) and compiled using Fiji distribution of ImageJ software (Schindelin et al., 2012) at a frame rate of 300 fps.”…"
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Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment
منشور في 2022"…We analyze the impact of a local anthropogenic emission inventory (EI) on model predictions, compared to the most commonly used EDGAR global emissions. The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Advanced direct air capture of CO<sub>2</sub> using air conditioning systems: a life cycle assessment
منشور في 2025"…A cradle-to-gate life cycle assessment (LCA) is conducted based on numerical modeling of the DAC-HVAC system. …"
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The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading
منشور في 2017"…Moreover, the plateau region in load-displacement curve decreases by increasing the number of corrugations and therefore the tube reaches its densification point earlier. …"
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
منشور في 2019"…However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. …"
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Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
منشور في 2024"…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO<sub>2</sub> column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO<sub>2</sub> levels before, during and after the tournament over Greater Doha. …"
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
منشور في 2019"…<h3>Background</h3><p dir="ltr">Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. …"
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A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
منشور في 2024"…Among the six countries, visibility in KWT is improving at 0.06 km/year, while visibility in IRQ is decreasing rapidly at the rate of -0.26 km/year. Keeping in account the overall trends over the decades to assess current visibility conditions, Visibility in KWT and QTR is improving at the fastest trend of + 0.15 and + 0.05 km/year respectively as compared to OMN, IRQ, UAE and KSA. …"
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Assessment Tools for Pulmonary Involvement in Patients with Ankylosing Spondylitis: Is Diaphragmatic Ultrasonography Correlated to Spirometry?
منشور في 2023"…Thus, the present study aimed to assess the accuracy of diaphragm ultrasound compared to spirometry in the screening of restrictive pulmonary disorders in radiographic SpA patients. …"
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Life cycle assessment of binary recycled ceramic tile and recycled brick waste-based geopolymers
منشور في 2022"…The life cycle impact assessment (LCIA) methodology using TRACI 2.0 and the GaBi databases is used to calculate the following impact categories: Global Warming Potential (GWP), Acidification Potential (AP), Eutrophication Potential (EP), Ozone Depletion Potential (ODP) and smog. …"
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Assessing Intra-Arab Trade Integration and Potential: Evidence from the Stochastic Frontier Gravity Model
منشور في 2022"…<p dir="ltr">This study aims to detect the presence of “<i>behind the border</i>” and <i>“beyond the border”</i> constraints on trade flows among Arab countries, using the stochastic frontier gravity model (SFGM) over the period of 1998 to 2015. …"
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Assessment of Knowledge, Attitude and Practice towards Sustainability Aspects among Higher Education Students in Qatar
منشور في 2022"…This value gradually decreases in attitudes and behaviors based on evaluating the pro-sustainability student responses. …"
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
منشور في 2023"…While those who had a decrease in their smoking level experienced a somehow healthier lifestyle regarding nutrition and other aspects.…"
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A Comprehensive Assessment of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewables and Energy Storage Systems
منشور في 2022"…<p dir="ltr">E-mobility has become of great interest for many countries worldwide, where the main objective is to decrease the dependency on fossil fuel-based transportation means and reduce CO<sub>2</sub> emissions generated from the transportation sector. …"
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3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios
منشور في 2020"…However, these environmental improvements diminished when 3DCP was coupled with the use of conventional reinforcement elements. Moreover, the use of an alternative concrete mixture in 3DCP showed a further decrease in the GWP, AP, EP, and FFD impact. …"