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A clustering metaheuristic for large orienteering problems
منشور في 2022"…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
منشور في 2013احصل على النص الكامل
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masterThesis -
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
منشور في 2021"…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …"
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …"
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Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures
منشور في 2024احصل على النص الكامل
doctoralThesis -
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Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
منشور في 2010"…Conclusions: Photostimulation of ChR2-transfected RVLM Phox2b neurons produces a vigorous stimulation of breathing accompanied by a small sympathetically mediated increase in BP. …"
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احصل على النص الكامل
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
منشور في 2024"…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …"
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The Effect of Soy Isoflavones on Steroid Metabolism
منشور في 2019"…In addition, 3βHSD2 was inhibited perhaps accounting for decreased A4 levels observed in females. The decreased DHEAS and A4 levels together with the inhibition of the 17,20 lyase activity of CYP17A1, may impact production of androgens in clinical conditions associated with androgen excess.…"
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Enhanced optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>-<sub><em>x</em></sub>S<sub><em>x</em></sub>S: A DFT study
منشور في 2025"…Here, we conduct systematic density functional theory calculations to study the effect of sulfur doping on the electronic and optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>. We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …"
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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
منشور في 2024"…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …"
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
منشور في 2002"…Similarly, chylomicron TAG, cholesterol, phospholipids and apo B48 as well as VLDL TAG, apo B48 and apo B 1 00 were also significantly increased. …"
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masterThesis -
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Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles
منشور في 2016"…Our drug delivery system consists of Pluronic-P105 micelles, targeted with folic acid moieties. …"
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
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احصل على النص الكامل
احصل على النص الكامل
masterThesis -
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Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
منشور في 2019"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"
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Long non-coding RNAs regulated NF-κB signaling in cancer metastasis: Micromanaging by not so small non-coding RNAs
منشور في 2022"…Mechanistically, NKILA has been consistently shown to inhibit NF-κB activation <i>via</i> inhibition of IκBα phosphorylation and the resulting suppression of EMT. …"
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro
منشور في 2017"…XTT cell viability assay, which detects the presence of metabolically active cells, was used to assess cell proliferation. A decrease in proliferation of KG-1 cells was observed upon treatment with both forms of vitamin E derivatives; however, β-T3 was more potent than γ-T3 in promoting cell death with lower IC50 values. …"
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احصل على النص الكامل
article